Olmesartan Medoxomil CAS 144689-63-4 Purity >99.5% (HPLC) API Factory

Short Description:

Chemical Name: Olmesartan Medoxomil

CAS: 144689-63-4

Purity: >99.5% (HPLC)

Appearance: White to Almost White Cyrstalline Powder

Angiotensin II Receptor Antagonist. Anti-Hypertensive

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Product Detail

Product Tags

Description:

Ruifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4

Chemical Properties:

Chemical Name	Olmesartan Medoxomil
Synonyms	4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester; CS-866
CAS Number	144689-63-4
CAT Number	RF-PI1730
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C29H30N6O6
Molecular Weight	558.60
Melting Point	180℃ (dec.)
Water Solubility	Insoluble in Water; Slightly Soluble in DMSO
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White to Almost White Cyrstalline Powder
Identification	IR, HPLC, UV: Must Conform to Reference Standard
Purity / Analysis Method	>99.5% (HPLC on the Anhydrous and Solvent-Free Basis)
Loss on Drying	<0.50%
Residue on Ignition	<0.10%
Related Substances
Olmesartan RRT 0.2	<0.50%
Olmesartan Medoxoil Related Compound A. RRT 0.7	<0.20%
Olefinic Impurity RRT 1.6	<0.50%
N-Alkyl Impurity RRT 3.4	<0.10%
Any Other Impurity	<0.10%
Total Impurities	<0.50%
Heavy Metals (as Pb)	<10ppm
pH of Solution (2%, W/V)	4.5 to 6.5
Test Standard	Enterprise Standard; USP Standard
Usage	API

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) is a potent and selective angiotensin II type 1 (AT(1)) receptor antagonist with IC50 of 66.2 μM., used in the treatment of high blood pressure. Used as an anti-hypertensive. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, Olmesartan inhibits the negative regulatory feedback on renin secretion. Olmesartan Medoxomil is a pro-drug that is de-esterified to the active metabolite, olmesartan. Olmesartan Medoxomil was launched in the US as Benicar, an orally administered treatment for hypertension.