DMDO-Cl CAS 80841-78-7 Purity >96.0% (GC) Olmesartan Medoxomil Intermediate Factory

Short Description:

Name: 4-Chloromethyl-5-methyl-1,3-dioxol-2-one

Synonyms: DMDO-Cl

CAS: 80841-78-7

Purity: >96.0% (GC)

Appearance: Colorless to Yellow Liquid

Intermediate of Olmesartan Medoxomil

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Product Detail

Product Tags

Description:

Ruifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4

Chemical Properties:

Chemical Name	4-Chloromethyl-5-methyl-1,3-dioxol-2-one
Synonyms	DMDO-Cl
CAS Number	80841-78-7
CAT Number	RF-PI1871
Stock Status	In Stock, Production Capacity 300 Tons/Year
Molecular Formula	C5H5ClO3
Molecular Weight	148.54
Boiling Point	93℃/2 mmHg
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Colorless to Yellow Liquid
Identification (GC)	The retention time of the major peak in the chromatogram of the sample corresponds ti that of the standard as obtained in purity and related substances
Purity / Analysis Method	>96.0% (GC)
Water (by Karl Fischer)	<0.50%
Impurity A	<1.50%
Impurity B	<0.50%
Impurity C	<3.00%
Impurity D	<4.00%
Impurity E	<0.10%
Refractive Index N20/D	1.476~1.482
Specific Gravity (20/20℃)	1.357~1.363
Proton NMR Spectrum	Conforms to Structure
Test Standard	Enterprise Standard
Usage	Intermediate of Olmesartan Medoxomil (CAS: 144689-63-4)

Route of Synthesis of 4-Chloromethyl-5-methyl-1,3-dioxol-2-one

Package & Storage:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

4-Chloromethyl-5-methyl-1,3-dioxol-2-one, (DMDO-Cl) (CAS: 80841-78-7) is an intermediate of Olmesartan Medoxomil (CAS: 144689-63-4. Olmesartan Medoxomil is a new selective and competitive nonpeptide angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion. Olmesartan Medoxomil was launched in the US as Benicar@, an orally administered treatment for hypertension.