Tirzepatide CAS 2023788-19-2 Purity (HPLC) ≥99.0% Peptide Content ≥85.0% High Quality

Short Description:

Chemical Name: Tirzepatide

CAS: 2023788-19-2

Purity (HPLC): ≥99.0%

Peptide Content: ≥85.0%

Appearance: White Powder

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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2023788-19-2 - Description:

Tirzepatide (CAS: 2023788-19-2) has a similar sequence to Semaglutide, and the lys side chain in the sequence has PEG modification, which is the functional group of the peptide, and can increase the water solubility of the sequence. Tirzepatide is a glucose-dependent insulin nutritive polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor dual agonist, is being developed for the treatment of type 2 diabetes and has entered the clinical stage. Purchase Tirzepatide, please e-mail: alvin@ruifuchem.com

2023788-19-2 - Chemical Properties:

Chemical Name	Tirzepatide
Peptide Sequence	Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-C20-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Synonyms	GIPGLP-1; GIP\GLP-1; LY3298176; Tilposide
Stock Status	In Stock, 950g
CAS Number	2023788-19-2
Molecular Formula	C225H348N48O68
Molecular Weight	4813.45 g/mol
Water Solubility	Soluble in Water
Storage Temperature	Freeze Dry at -20℃ and Store in Cool dry place (Away From Light)
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	Synthetic Peptide Anti-Diabetic
Caution	Not For Human Use. For Laboratory Research Use Only.
Brand	Ruifu Chemical

2023788-19-2 - Specifications:

Items	Specifications	Results
Appearance	White Powder	White Powder
Solubility	Soluble in Water	Soluble in Water
Purity (HPLC)	≥99.0%	99.30%
Related Substance (HPLC)	Any Individual Impurity≤1.0%	0.43%
Amino Acid Analysis
Asp	1.6~2.4	2.0
Tyr	1.6~2.4	2.1
Lys	1.6~2.4	2.0
Ile	2.4~3.6	3.1
Leu	1.6~2.4	2.0
Val	0.8~1.2	1.0
Thr	1.6~2.4	2.0
Phe	1.6~2.4	2.0
Ser	4.0~6.0	4.6
Ala	3.2~4.8	4.0
Gly	3.2~4.8	4.0
Glu	3.2~4.8	4.0
Pro	3.2~4.8	4.0
Aib	N/A	-- --
AEEA	N/A	-- --
Sodium	<5.0%	1.01%
Peptide Content	≥85.0%	91.38%
Water Content (Karl Fischer)	≤10.0%	2.74%
Residual Solvents
Acetonitrile	≤410ppm	105.83ppm
Methanol	≤3000ppm	Not Detected
Bacterial Endotoxins	<10EU/mg	Conforms
Microbial Limits
Total Aerobic Microbial Count	≤1000cfu/g	Conforms
Total Yeast and Mold Count	≤200cfu/g	Conforms
MS (ESI)	4813.45±1.0	4813.93
pH (5.0mg/ml)	6.0-8.0	6.89
Assay (HPLC)	95.0%~105.0% (on Anhydrous and Salt-Free Substance Basis)	103.43%
Conclusion	The product has been tested and complies with the Enterprise Standard

(1) It is not derived from human, animal or plant.
(2) The above material is to be used exclusively for in vitro laboratory research purposes only. It has no commercial resale value. It
is NOT for Human or Animal Consumption.
(3) The material is NOT hazardous, nor infectious. The material is NOT an immunogen.
It is NOT a drug or a controlled substance.
(4) It does NOT contain any animal or cell culture derived products or additives such as Albumin or Serum. The Material is NON-HAZARDOUS
For Laboratory Research Use Only.

2023788-19-2 - Note:

The listed products which involve patents, are only for research and development, and not used for sales.
Regulated products will be sold in strict accordance with the laws of China and the laws of the buyer's country.
All products are not for human use ,and all risks associated with the sale to the country that constitutes a patent infringement shall be borne by the buyer.

2023788-19-2 - Package/Storage/Shipping:

Package: Vial, 1g/vial (accurate to the milligram as required); or according to customer's requirement.
Storage Condition: Keep the vial tightly closed. Store in a cool, dry (-20℃) warehouse. Keep away from light; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

2023788-19-2 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

2023788-19-2 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

2023788-19-2 - Application:

Tirzepatide (CAS: 2023788-19-2) is a glucose-dependent insulin nutritive polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor dual agonist. Tirzepatide has neuroprotective effects and can be used in the study of type 2 diabetes, diabetes-related neuropathy and obesity.

Tirzepatide is in phase 3 clinical development at Eli Lilly and Company for blood glucose management in adults with type 2 diabetes, chronic weight management, and obesity-related heart failure with preserved ejection fraction.

It works to stimulate first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose-dependent manner. Tirzepatide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake, 4 and reduce body weight in patients with type 2 diabetes.