N2-Trityl Olmesartan Acid CAS 752179-89-8 Purity >98.0% (HPLC) Olmesartan Medoxomil Intermediate Factory

Short Description:

Chemical Name: N2-Trityl Olmesartan Acid

CAS: 752179-89-8

Purity: >98.0% (HPLC)

Appearance: White to Off-White Powder

Intermediate of Olmesartan Medoxomil

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Product Detail

Product Tags

Description:

Ruifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4

Chemical Properties:

Chemical Name	N2-Trityl Olmesartan Acid
Synonyms	Trityl Olmesartan Acid (N2); Olmesartan N2-Trityl Impurity; 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-Carboxylic Acid; 4-(2-Hydroxypropan-2-yl)-2-Propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-Imidazole-5-Carboxylic Acid
CAS Number	752179-89-8
CAT Number	RF-PI1876
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C43H40N6O3
Molecular Weight	688.82
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White to Off-White Powder
Purity / Analysis Method	>98.0% (HPLC)
Loss on Drying	<1.00%
Residue on Ignition	<0.50%
Single Impurity	<1.00%
Total Impurities	<2.00%
Heavy Metals (as Pb)	<20ppm
Test Standard	Enterprise Standard
Usage	Intermediate of Olmesartan Medoxomil (CAS: 144689-63-4)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

N2-Trityl Olmesartan Acid (CAS: 752179-89-8) is an intermediate in the synthesis of Olmesartan Medoxomil (CAS: 144689-63-4) related compounds. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. Olmesartan Medoxomil is a prodrug of Olmesartan, is an angiotensin II type 1 receptor (AT1) inhibitor that inhibits negative regulatory feedback on renin secretion, decreasing secretion of aldosterone and resulting in decreased peripheral vascular resistance (vasodilation). This compound exhibits antihypertensive, cardioprotective, vasodilatory, and anti-inflammatory activities. Olmesartan Medoxomil may be used alone or in combination with other antihypertensive agents. In comparative clinical studies in patients with essential hypertension, Olmesartan reduced sitting cuff diastolic blood pressure significantly more than Losartan, Valdesartan and Ibesartan, while reductions in systolic blood pressure were similar for all treatments.