Sodium Valproate (VPA) CAS 1069-66-5 API Factory High Purity

Short Description:

Chemical Name: Sodium Valproate (VPA) 

Synonyms: Valproic Acid Sodium Salt

CAS: 1069-66-5

Appearance: White or Almost White Crystalline Powder, Hygroscopic

Assay: 98.5%~101.0% (Titration) 

A Broad-Spectrum Anti-Epileptic Drug Usually Well Tolerated

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


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Description:

Manufacturer Commercial Supply with High Purity and Stable Quality
Chemical Name: Sodium Valproate (VPA) 
CAS: 1069-66-5 

Chemical Properties:

Chemical Name Sodium Valproate
Synonyms VPA; Valproic Acid Sodium Salt; Sodium 2-Propylpentanoate 
CAS Number 1069-66-5
CAT Number RF-API14
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H15NaO2
Molecular Weight 166.20
Melting Point 300℃
Density 1.0803 g/cm3
Water Solubility Soluble in Water
Shipping Condition Under Ambient Temperature
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White or Almost White Crystalline Powder, Hygroscopic
Identification Infrared Spectrum
By RT comparison
Reactions of Sodium Salt
Solubility Very Soluble in Water, Freely Soluble in Ethanol 
Acidity or Alkalinity According to EP Criterions
Clarity & Color of Solution According to EP Criterions
Heavy Metals ≤20ppm
Sulfates ≤200ppm
Chloride ≤200ppm
Loss on Drying ≤2.0%
Any Impurity ≤0.10% (GC)
Total Impurities ≤0.30% (GC)
Assay 98.5%~101.0% (Titration) 
Test Standard European Pharmacopeia (EP)
Usage Active Pharmaceutical Ingredient (API)

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

12

Application:

Sodium Valproate (CAS: 1069-66-5) is an anticonvulsant and effective agent for control of both absence and primarily generalized tonic-clonic seizures. Valproic acid sodium salt (Sodium Valproate) is a histone deacetylase (HDAC) inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Sodium Valproate (CAS: 1069-66-5) is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

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