Ropivacaine Hydrochloride Monohydrate CAS 132112-35-7 API USP Standard High Purity

Short Description:

Chemical Name: Ropivacaine Hydrochloride Monohydrate

Synonyms: Ropivacaine HCl.H2O

CAS: 132112-35-7

Appearance: White Crystalline Powder

Assay: 98.5%~101.0%

Long-Acting Amide Local Anaesthetic Agent 

API USP Standard,  Commercial Production

Inquiry: alvin@ruifuchem.com


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Description:

Manufacturer with High Purity and Stable Quality
Chemical Name: Ropivacaine Hydrochloride Monohydrate
Synonyms: Ropivacaine HCl.H2O
CAS: 132112-35-7  
An anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly
API USP Standard, High Quality, Commercial Production

Chemical Properties:

Chemical Name Ropivacaine Hydrochloride Monohydrate
Synonyms Ropivacaine HCl.H2O
CAS Number 132112-35-7
CAT Number RF-API42
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C17H26N2O.ClH.H2O
Molecular Weight 328.88
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Crystalline Powder
Identification (1) It should be positive reaction 
(2) IR: Match with the reference standard
Color The absorbance at 405nm is not more than 0.030 
The absorbance at 436nm is not more than 0.025 
Solubility Soluble in Water
pH 4.5~6.0
Clarity Should be Clear
Water 5.0%~6.0%
Specific Rotation -210° ~ -255° (at 365 nm)
Heavy Metals ≤10ppm
Limit of Ropivacaine Related Compound A ≤10ppm
Related Compounds  
Bupivacaine ≤0.20%
Other Individual Impurity ≤0.10%
Total Impurity ≤0.50%
Enantiomeric Purity ≤0.50%
Residual Solvents
Ethanol ≤0.50%
Acetone ≤0.50%
4-Methyl-2-Pentanone ≤0.50%
2,6-Dimethylaniline ≤10ppm
Assay 98.5%~101.0%
Test Standard United States Pharmacopeia (USP) Standard
Usage Active Pharmaceutical Ingredient (API)

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Ropivacaine Hydrochloride Monohydrate (CAS: 132112-35-7) with high quality.

Ropivacaine is a long-acting amide local anaesthetic agent and first produced as a pure enantiomer. It produces effects similar to other local anaesthetics via reversible inhibition of sodium ion influx in nerve fibres. Ropivacaine is less lipophilic than bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity.

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