Sitagliptin Phosphate Intermediate Impurity CAS 769195-26-8 Purity >99.0% (HPLC)

Short Description:

Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate

CAS: 769195-26-8

Purity: >99.0% (HPLC)

Appearance: White to Off-White Powder

Intermediate / Impurity of Sitagliptin Phosphate

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Product Detail

Product Tags

769195-26-8 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate (CAS: 769195-26-8) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

769195-26-8 - Chemical Properties:

Chemical Name	Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate
Synonyms	Sitagliptin Impurity 17; 2,4,5-Trifluoro-β-Oxo-Benzenebutanoic Acid Methyl Ester
CAS Number	769195-26-8
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C11H9F3O3
Molecular Weight	246.18
Melting Point	40.0~41.0℃
Boiling Point	273.3±35.0℃
Density	1.330±0.06 g/cm3
Storage Condition	Under Inert Gas (Nitrogen or Argon) at 2~8℃
COA & MSDS	Available
Place of Origin	Shanghai, China
Brand	Ruifu Chemical

769195-26-8 - Specifications:

Item	Specifications
Appearance	White to Off-White Powder
Purity / Analysis Method	>99.0% (HPLC)
Loss on Drying	<1.00%
Single Impurity	<0.50%
Total Impurities	<1.00%
Proton NMR Spectrum	Conforms to Structure
Test Standard	Enterprise Standard
Usage	Intermediate / Impurity of Sitagliptin Phosphate

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

769195-26-8 - Application:

Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate (CAS: 769195-26-8) is a useful synthetic intermediate in the synthesis of Sitagliptin (CAS: 486460-32-6), Sitagliptin Phosphate (CAS: 654671-78-0). Sitagliptin Phosphate is dipeptidyl peptidase Ⅳ(DDP-4) inhibitor class of drugs developed by the German Merck company and firstly obtained the US Food and Drug Administration approval for the treatment of type 2 diabetes, is a new antidiabetic drug, can improve the body's own ability to reduce high blood glucose levels, and the relatively increase naturally occurring incretin by inhibiting the activity of this enzyme, including the levels of glucagon-like peptide 1 and glucose-dependent insulinotropic peptide, thereby triggering the pancreas to improve insulin production and stop glucose production in liver, and ultimately reduce the clinical effect of blood glucose concentration.