Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2 Telmisartan Intermediate

Short Description:

Name: Methyl 2-[4-(Bromomethyl)phenyl]benzoate 

CAS: 114772-38-2

Purity: >99.0% (HPLC) 

Appearance: White to Light Yellow Crystalline Powder

Intermediate of Telmisartan (CAS: 144701-48-4) 

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401   


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114772-38-2 - Chemical Properties:

Chemical Name Methyl 2-[4-(Bromomethyl)phenyl]benzoate
Synonyms 2-[4-(Bromomethyl)phenyl]benzoic Acid Methyl Ester; Methyl 4'-(Bromomethyl)biphenyl-2-Carboxylate; 4'-(Bromomethyl)biphenyl-2-Carboxylic Acid Methyl Ester; Telmisartan Intermediate
CAS Number 114772-38-2
Stock Status In Stock, Production Capacity 150MT/Year
Molecular Formula C15H13BrO2
Molecular Weight 305.17
Density 1.374±0.06 g/cm3
Melting Point 52.0 to 57.0℃
Solubility Soluble in Toluene
COA & MSDS Available
Place of Origin  Shanghai, China
Brand Ruifu Chemical

114772-38-2 - Specifications:

Item Specifications Results
Appearance White to Light Yellow Crystalline Powder Conforms
Clarity Colorless and Transparent, Without Foreign Substances Conforms
Purity / Analysis Method >99.0% (HPLC)   99.7%
Assay / Analysis Method 97.0%~103.0% 99.5%
Melting Point 52.0~57.0℃ 56.1℃ 
Loss on Drying <0.50% 0.05%
Residue on Ignition <0.20% 0.06%
Single Impurity <0.50% 0.24%
Total Impurities <1.00%  0.30%
Heavy Metals (as Pb) <20ppm <20ppm
NMR Spectrum Conforms to Structure Conforms
Test Standard Enterprise Standard Conforms
Usage Intermediate of Telmisartan (CAS: 144701-48-4)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture




114772-38-2 - Risk and Safety:

Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code 2916399090

114772-38-2 - Application:

Methyl 2-[4-(Bromomethyl)phenyl]benzoate (CAS: 114772-38-2), pharmaceutical intermediates, used in the production of sartan series APIs. Methyl 2-[4-(Bromomethyl)phenyl]benzoate is an intermediate of Telmisartan (CAS: 144701-48-4). Telmisartan is an angiotensin II receptor blocker (ARB) that has high affinity for the angiotensin II receptor type 1 (AT1).Telmisartan interferes with the binding of angiotensin II to AT1 receptors in vascular smooth muscle and thus inhibits the vasoconstricting action of angiotensin II. Telmisartan was originally formulated by the German pharmaceutical company Boehringer Ingelheim. Telmisartan was launched in the US for the treatment of hypertension. Used alone or in combination with other classes of antihypertensives for the treatment of hypertension.

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