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4-Phenoxyphenylboronic Acid CAS 51067-38-0 Ibrutinib Intermediate Purity >99.0% (HPLC) Featured Image
  • 4-Phenoxyphenylboronic Acid CAS 51067-38-0 Ibrutinib Intermediate Purity >99.0% (HPLC)
  • 4-Phenoxyphenylboronic Acid CAS 51067-38-0 Ibrutinib Intermediate Purity >99.0% (HPLC)

4-Phenoxyphenylboronic Acid CAS 51067-38-0 Ibrutinib Intermediate Purity >99.0% (HPLC)

Short Description:

Chemical Name: 4-Phenoxyphenylboronic Acid 

CAS: 51067-38-0

Purity: >99.0% (HPLC)

Appearance: White to Off-White Powder 

Intermediate of Ibrutinib (CAS: 936563-96-1) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401    

E-Mail: alvin@ruifuchem.com


Product Detail

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Intermediates of Ibrutinib:

Ibrutinib CAS 936563-96-1                           
3-Hydroxypiperidine CAS 6859-99-0 
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxybenzoic Acid  CAS 2215-77-2
4-Phenoxyphenylboronic Acid CAS 51067-38-0
4-Aminopyrazolo[3,4-d]pyrimidine CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pyrimidine  CAS 151266-23-8 
Ibrutinib Deacryloylpiperidine CAS 330786-24-8 
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Chemical Properties:

Chemical Name 4-Phenoxyphenylboronic Acid
Synonyms 4-Phenoxybenzeneboronic Acid
CAS Number 51067-38-0
Stock Status In Stock, Production Scale Up to 25 Tons/Month
Molecular Formula C12H11BO3
Molecular Weight 214.03 
Melting Point 141.0~145.0℃ (lit.)
Density 1.23±0.10 g/cm3
Solubility Soluble in Methanol
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder
Purity / Analysis Method >99.0% (HPLC)
Loss on Drying <0.50%
Residue on Ignition <0.50%
Total Impurities <0.50%
Heavy Metals (as Pb) <20ppm
Infrared Spectrum Conforms to Structure
1H NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates; Intermediate of Ibrutinib (CAS: 936563-96-1)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

1

FAQ:

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51067-38-0 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
HS Code 2931900090
Hazard Class IRRITANT

51067-38-0 - Application:

4-Phenoxyphenylboronic Acid (CAS: 51067-38-0) is a kind of chemical intermediates with a wide range of applications, widely used in the synthesis of pharmaceuticals, dyes and other fine chemical products. It's an intermediate of anticancer drugs, such as Ibrutinib (CAS: 936563-96-1). Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). 4-Phenoxyphenylboronic Acid can be used as a reactant: In the Suzuki-Miyaura coupling reaction to synthesize aryl derivatives via C-C bond formation by reacting with different aryl halides over a palladium catalyst.

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