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3-Hydroxypiperidine CAS 6859-99-0 Ibrutinib Intermediate Purity >99.0% (GC) Featured Image
  • 3-Hydroxypiperidine CAS 6859-99-0 Ibrutinib Intermediate Purity >99.0% (GC)
  • 3-Hydroxypiperidine CAS 6859-99-0 Ibrutinib Intermediate Purity >99.0% (GC)

3-Hydroxypiperidine CAS 6859-99-0 Ibrutinib Intermediate Purity >99.0% (GC)

Short Description:

Chemical Name: 3-Hydroxypiperidine

Synonyms: 3-Piperidinol 

CAS: 6859-99-0

Purity: >99.0% (GC)

White or Light Yellow Crystalline Powder  

Intermediate of Ibrutinib (CAS: 936563-96-1)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 3-Hydroxypiperidine (CAS: 6859-99-0) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 3-Hydroxypiperidine, Please contact: alvin@ruifuchem.com

Intermediates of Ibrutinib:

Ibrutinib CAS 936563-96-1                           
3-Hydroxypiperidine CAS 6859-99-0 
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxybenzoic Acid  CAS 2215-77-2
4-Phenoxyphenylboronic Acid CAS 51067-38-0
4-Aminopyrazolo[3,4-d]pyrimidine CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pyrimidine  CAS 151266-23-8 
Ibrutinib Deacryloylpiperidine CAS 330786-24-8 
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Chemical Properties:

Chemical Name 3-Hydroxypiperidine  
Synonyms 3-Piperidinol; Piperidin-3-ol; (±)-3-Piperidinol; (±)-3-Hydroxypiperidine
Stock Status In Stock, Commercial Production  
CAS Number 6859-99-0 
Molecular Formula C5H11NO
Molecular Weight 101.15 g/mol
Melting Point 57.0 to 61.0℃ 
Boiling Point 67.0~69.0℃/2 mmHg
Flash Point >100℃(212°F)  
Density 1.016±0.06 g/cm3 
Sensitive Air Sensitive & Hygroscopic  
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White or Light Yellow Crystalline Powder   Complies             
Purity / Analysis Method        >99.0% (GC)  99.56%
Water by Karl Fischer  <1.00% 0.22%
Total Impurities <1.00% 0.44%
1 H NMR Spectrum Consistent with Structure Complies 
Conclusion The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

6859-99-0 - Safety Information:

Risk Codes
R34 - Causes burns
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S27 - Take off immediately all contaminated clothing.
UN IDs UN 3263 8/PG 2
WGK Germany 3
HS Code 2933399030
Hazard Class 8
Packing Group III

6859-99-0 - Application:

3-Hydroxypiperidine (CAS: 6859-99-0) is used as an organic synthesis intermediate, pharmaceutical intermediate, or chemical reagent. 3-Hydroxypiperidine is a piperidine derivative, an organic heterocyclic amine widely used as a basis and reagent for the synthesis of organic compounds, including pharmaceuticals.
3-Hydroxypiperidine is an important drug intermediate, in lowering blood pressure, anti-tumor, anti-coccidiosis and many other high value-added medical fields have been applied.
3-Hydroxypiperidine is usually used for synthesis of unsymmetrical ureas, synthesis of piperidine nucleoside analogs, fluorination reactions, synthesis of substituted pyridines.
3-Hydroxypiperidine can be used as an Intermediate of Ibrutinib (CAS: 936563-96-1). Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL).  

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