2-Bromo-6-Methoxynaphthalene CAS 5111-65-9 Purity >99.0% (GC) Naproxen Nabumetone Intermediate

Short Description:

Chemical Name: 2-Bromo-6-Methoxynaphthalene  

CAS: 5111-65-9

Purity: >99.0% (GC)

Appearance: Yellowish to Off-White Crystalline

Intermediate in the Synthesis of Naproxen, Nabumetone 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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5111-65-9 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 2-Bromo-6-Methoxynaphthalene (CAS: 5111-65-9) with high quality, intermediate in the synthesis of Naproxen (CAS: 22204-53-1) and Nabumetone (CAS: 42924-53-8). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Please contact: alvin@ruifuchem.com

Naproxen & Nabumetone Intermediates:

5111-65-9 - Chemical Properties:

Chemical Name 2-Bromo-6-Methoxynaphthalene
Synonyms BMN; 2-Methoxy-6-Bromonaphthalene; 6-Methoxy-2-bromonaphthalene; 6-Bromo-2-Naphthyl Methyl Ether; 6-Bromo-2-Methoxynaphthalene
Impurity  Naproxen EP Impurity N; Naproxen Impurity N
Stock Status In Stock, Commercial Production
CAS Number 5111-65-9
Molecular Formula C11H9BrO 
Molecular Weight 237.10 g/mol
Melting Point 107.0~111.0℃(lit.)   
Boiling Point 160.0~164.0℃/3 mmHg 
Solubility  Soluble in DMSO. Insoluble in Water 
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical

5111-65-9 - Specifications:

Items Specifications  Results
Appearance Yellowish to Off-White Crystalline  Off-White Crystalline 
Melting Point 107.0~111.0℃ 108.0~109.0℃
Water by Karl Fischer  <0.10% 0.03% 
Residue on Ignition <0.20% 0.05%
Purity / Analysis Method >99.0% (GC) 99.5%
Infrared Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Naproxen (CAS: 22204-53-1) & Nabumetone (CAS: 42924-53-8)

5111-65-9 - Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Store away from strong oxidizing agents. 
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

5111-65-9 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

5111-65-9 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

5111-65-9 - Risk and Safety:

Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S37/39 - Wear suitable gloves and eye/face protection
WGK Germany 3
HS Code 2909309090

5111-65-9 - Application:

2-Bromo-6-Methoxynaphthalene (CAS: 5111-65-9), intermediate in the synthesis of Naproxen (CAS: 22204-53-1) and Nabumetone (CAS: 42924-53-8).
Naproxen is a non-steroidal anti-inflammatory drug for the relief of fever and inflammation and pain associated with arthritis or other symptoms, Naproxen has anti-inflammatory, antipyretic and analgesic effects. Naproxen plays a role by inhibiting the cyclooxygenase, which generates prostaglandin and is one kind of enzymes related to inflammatory mediators.
Nabumetone is a long acting non-steroidal anti-inflammatory drug (NSAID), prescribed for managing pain associated with acute/chronic rheumatoid arthritis, osteoarthritis and other musculoskeletal disorders. Nabumetone is a non-steroidal anti-inflammatory drug used clinically, and its biotransformation includes the major active metabolite 6-methoxy-2-naphthylacetic acid (6-MNA). 

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