Tris Base CAS 77-86-1 Purity ≥99.50% (Titration) Biological Buffer Molecular Biology Grade

Tris Base (CAS: 77-86-1), or Tris(hydroxymethyl)aminomethane, or known during medical use as Trometamol or THAM. It is extensively used  as a zwitterionic biological buffer in biochemistry and molecular biology research, and enzymatic research. Tris base is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0~9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins. Tris buffer, only nucleic acids and proteins are widely used as solvents.  Tris is used for protein crystal growth under different pH conditions. Tris buffer having a low ionic strength can be used nematode (C. elegans) is formed lamin (lamin) intermediate fibers. Tris is a major component of protein electrophoresis buffer. Tris for the preparation of a surfactant, a vulcanization accelerator, and some drug intermediates.