Bis-Tris CAS 6976-37-0 Purity >99.0% (Titration) Biological Buffer Ultra Pure
Ruifu Chemical is the leading manufacturer of Bis-Tris (CAS: 6976-37-0) with high quality, commercial production, Good's buffer component for biological research. Welcome to order. Please contact: alvin@ruifuchem.com
| Chemical Name | Bis-Tris |
| Synonyms | Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane; Bis(2-hydroxyethyl)iminotris(hydroxymethyl)methane; 2,2-Bis(hydroxymethyl)-2,2′,2''-Nitrilotriethanol; Bis-Tris Methane |
| CAS Number | 6976-37-0 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C8H19NO5 |
| Molecular Weight | 209.24 |
| Store Under Inert Gas | Store Under Inert Gas |
| Sensitive | Hygroscopic. Air Sensitive |
| Solubility in Water | Completely Soluble in Water, Almost Transparency |
| Melting Point | 102.0~106.0℃(lit.) |
| Density | 1.346±0.06 g/cm3 |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Product Categories | Biological Buffers |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Grade | Ultra Pure |
| Appearance | White Crystalline Powder |
| Purity / Analysis Method | >99.0% (Titration on Dried Basis) |
| Melting Point | 102.0~106.0℃ |
| Water (by Karl Fischer) | <0.50% |
| Loss on Drying | <0.50% 20 ℃ (HV) |
| Residue on Ignition | <0.20% |
| Insoluble Matter | Passes Filter Test |
| Heavy Metals (as Pb) | ≤5ppm |
| Iron (Fe) | ≤5ppm |
| UV A280nm | ≤0.04 (1 cm/0.1 M in Water) |
| UV A340nm | ≤0.02 (1 cm/0.1 M in Water) |
| pH | 9.5~11.0 (1.0M aqueous Solution at 25℃) |
| Useful pH Range | 5.8~7.2 |
| pKa (25℃) | 6.45~6.65 |
| Solubility | Clear and Complete (0.1M in H2O) |
| Chloride (Cl-) | ≤50 mg/kg |
| Sulfate (SO42-) | ≤50 mg/kg |
| Al | ≤5 mg/kg |
| As | ≤0.1 mg/kg |
| Ba | ≤5 mg/kg |
| Bi | ≤5 mg/kg |
| Ca | ≤10 mg/kg |
| Cd | ≤5 mg/kg |
| Co | ≤5 mg/kg |
| Cr | ≤5 mg/kg |
| Cu | ≤5 mg/kg |
| Iron (Fe) | ≤5 mg/kg |
| K | ≤50 mg/kg |
| Li | ≤5 mg/kg |
| Mg | ≤5 mg/kg |
| Mn | ≤5 mg/kg |
| Mo | ≤5 mg/kg |
| Na | ≤50 mg/kg |
| Ni | ≤5 mg/kg |
| Sr | ≤5 mg/kg |
| Infrared Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | Biological Buffer; Good's Buffer Component for Biological Research |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R21/22 - Harmful in contact with skin and if swallowed.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S22 - Do not breathe dust.
WGK Germany 3
FLUKA BRAND F CODES 10-23
TSCA Yes
HS Code 2922199090
Bis-Tris (CAS 6976-37-0) is a commonly used biological buffer, used in biochemistry and molecular biology. Bis-Tris is an inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant. It is a bis(2-hydroxyethyl)amine and Tris family buffer. Bis-Tris is of an Ultra Pure Grade. Bis-tris methane is an organic tertiary amine with labile protons having a pKa of 6.46 at 25℃. It is an effective buffer between the pH 5.8~7.2. Bis-Tris binds strongly to Cu and Pb ions as well as, weakly, to Mg, Ca, Mn, Co, Ni, Zn and Cd. Bis-Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing.
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