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Popular Design for Zoledronic Acid Monohydrate - Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality – Ruifu Featured Image
  • Popular Design for Zoledronic Acid Monohydrate - Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality – Ruifu

Popular Design for Zoledronic Acid Monohydrate - Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality – Ruifu

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To be a result of ours specialty and service consciousness, our enterprise has won an excellent status between buyers all around the globe for 6-(Chloromethyl)uracil, Formula Weight 654.81, Molecular Formula C5H14Cl2N2, We're prepared to present you with the most effective ideas over the designs of the orders in a qualified way for those who need. While in the meantime, we continue to keep on producing new technologies and building new designs so as to help make you ahead from the line of this small business.
Popular Design for Zoledronic Acid Monohydrate - Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality – Ruifu Detail:

Supply Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3

Chemical Name Sitagliptin Phosphate Monohydrate
Synonyms (R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate
CAS Number 654671-77-9
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C16H20F6N5O6P
Molecular Weight 523.3240802
Melting Point 202.0~204.0℃
Water Solubility Soluble in Water
Specific Rotation -18.0°~-23.0° (C=1, Water)
Brand Ruifu Chemical
Item Specifications
Appearance White to Off-White Crystalline Powder
Identification by HPLC The retention time of sample is concordant with reference standard
IR-Infrared Spectrum The IR Absorption Spectrum of the sample shall be concordant with that of standard spectrum
Phosphate Complies
Purity / Analysis Method >99.0% (HPLC on the dried basis) 
Water Content (K.F) 3.3%~4.4%
Residue on Ignition ≤0.20%
Sulphate ≤0.02%
Chloride ≤0.05%
Chiral Impurity <0.50%
Related Substances
Single Impurity <0.50%
Total Impurities <1.0%
Ethyl Acetate <0.50%
Heavy Metals <20ppm
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

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Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9), a new drug for the treatment of type 2 diabetes. In August 2009, the drug was approved by the European Union as a first-line drug for the treatment of type 2 diabetes. Sitagliptin Phosphate is the first FDA-approved dipeptidyl peptidase-IV inhibitor to be used in the treatment of type 2 diabetes by far, under the trade name Januvia. Dipeptidylpeptidase Ⅳ (DPP-Ⅳ) rapidly and effectively degrades GLP-1, GLP-1, which is the most effective stimulator of insulin production and secretion Therefore, inhibition of DPP-IV can enhance the role of endogenous GLP-1, thereby increasing blood insulin levels, thereby reducing and maintaining blood glucose levels in diabetic patients. At present, medicine has confirmed that DPP-IV inhibitor is a new type of anti-diabetic drug, and clinical results show that the drugs have a good hypoglycemic effect. Because GLP-1 plays a glucose-dependent role in promoting insulin production and secretion, common adverse reactions such as hypoglycemia and weight gain caused by the use of antidiabetic drugs do not occur.

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We have now numerous great personnel members good at advertising, QC, and working with kinds of troublesome dilemma from the creation course of action for Popular Design for Zoledronic Acid Monohydrate - Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality – Ruifu , The product will supply to all over the world, such as: Cambodia, Saudi Arabia, St. Petersburg, Our mission is to deliver consistently superior value to our customers and their clients. This commitment permeates everything we do, driving us to continuously develop and improve our products and the processes to fulfill your needs.
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