Olopatadine Hydrochloride CAS 140462-76-6 Purity >99.0% (HPLC)

Short Description:

Chemical Name: Olopatadine Hydrochloride 

CAS: 140462-76-6

Purity: >99.0% (HPLC) 

Appearance: White Crystalline Powder 

API High Quality, Commercial Production

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E-Mail: alvin@ruifuchem.com


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Description:

Leading Supplier of Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Olopatadine Hydrochloride 
Synonyms Olopatadine HCl; (Z)-11-[3-(Dimethylamino)propylidene]-6,11-Dihydrodibenz[b,e]oxepin-2-Acetic Acid Hydrochloride; Olopax; Olopine; Pataday; Patadine; Patanase; Patanol; Pazeo  
CAS Number 140462-76-6 
CAT Number RF2699
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C21H23NO3·HCl  
Molecular Weight 373.88  
Melting Point 242.0~245.0℃
Density   1.221 g/cm3 
Water Solubility H2O: ≥20 mg/mL
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Crystalline Powder
Identification 1, Reaction of Chlorides 2, IR 3, HPLC
Purity / Analysis Method >99.0% (HPLC) 
Purity / Analysis Method 98.5~102.5% (Titration by AgNO3) 
Acidity (pH) 2.0~4.0 (1% Solution in Water)
Loss on Drying <0.50% (Dry it at 105℃ for 3h)
Residue on Ignition <0.20%
Heavy Metals ≤10ppm
Related Suhstances (by HPLC) 
E-Isomer <0.15%
α-Hydroxy Olpatadine <0.20%
Any Unknown Impurities <0.20%
Total Impurities <0.50%
Infrared Spectrum Conforms to Structure
Test Standard Conformsto USP34
Usage API; Antihistamine; Antiallergic

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

Olopatadine Hydrochloride (CAS: 935-56-8) is a mast cell histamine release inhibitor and a selective H1 receptor antagonist. Olopatadine Hydrochloride tablets/capsules are used for allergic rhinitis, urticaria, pruritus (eczema, dermatitis, pruritus, psoriasis vulgaris, exudative erythema multiforme). Olopatadine Hydrochloride eye drops are used to treat the symptoms of allergic conjunctivitis. Olopatadine Hydrochloride eye drops combined with Praprofen eye drops have a remarkable clinical effect in the treatment of allergic conjunctivitis. Olopatadine Hydrochloride is an ophthalmic antihistamine that inhibits release of histamine from mast cells and is a relatively selective histamine H1 antagonist. It inhibits type 1 immediate hypersensitivity reactions. Olopatadine Hydrochloride is indicated in the temporary relief of itching caused by allergic conjunctivitis. H1 antagonists have an established and valued place in the symptomatic treatment of various immediate hypersensitivity reactions. In addition, the central properties of some of the series are of therapeutic value for suppressing motion sickness or for sedation.

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