Isoxepac CAS 55453-87-7 Purity >99.0% (HPLC) Olopatadine Hydrochloride Intermediate Factory

Short Description:

Chemical Name: Isoxepac

6,11-Dihydro-11-Oxodibenzo[b,e]oxepin-2-Acetic Acid

CAS: 55453-87-7

Purity: >99.0% (HPLC) 

Appearance: Light-Yellow to Off-White Crystalline Powder

Intermediate of Olopatadine Hydrochloride CAS 140462-76-6

High Quality, Commercial Production

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Leading Supplier of Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Isoxepac 
Synonyms 6,11-Dihydro-11-Oxodibenzo[b,e]oxepin-2-Acetic Acid; 6H-11-Oxodibenzo[b,e]oxepin-2-Acetic Acid; HP 549 
Impurity  Olopatadine Impurity 3; Olopatadine USP Related Compound C; Olapatadine EP Impurity C
CAS Number 55453-87-7 
CAT Number RF2697
Stock Status In Stock, Production Capacity 30 Tons per Month  
Molecular Formula C16H12O4 
Molecular Weight 268.27  
Melting Point 137.0~142.0℃
Density 1.39 g/cm3
Solubility  Soluble in Methanol
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Light-Yellow to Off-White Crystalline Powder
Identification HPLC / UV
Purity / Analysis Method >99.0% (HPLC) 
Melting Point 137.0~142.0℃
Water (by Karl Fischer) <0.50%
Loss on Drying <0.50%
Heavy Metals <20ppm
Total Impurities <1.00%
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Intermediate / Impurity of Olopatadine Hydrochloride (CAS: 140462-76-6)

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

Isoxepac (CAS: 55453-87-7) is an intermediate of Olopatadine Hydrochloride (CAS: 140462-76-6). Olopatadine Hydrochloride is a mast cell histamine release inhibitor and a selective H1 receptor antagonist. Olopatadine Hydrochloride tablets/capsules are used for allergic rhinitis, urticaria, pruritus (eczema, dermatitis, pruritus, psoriasis vulgaris, exudative erythema multiforme). Olopatadine Hydrochloride eye drops are used to treat the symptoms of allergic conjunctivitis. Olopatadine Hydrochloride is an anti-allergic drug. It has the dual effects of inhibiting the release of histamine and selectively antagonizing HI receptors, and has no central nervous system inhibition and cardiac toxic side effects that are common with HI receptor antagonist antiallergic drugs. The drug can not only inhibit the release of histamine from mast cells, but also antagonize H1 receptors more selectively, and has no effect on α adrenergic receptors, dopamine receptors, and M1 and M2 receptors. Among them, the side effects of the central nervous system are few, is a new generation of antiallergic drugs of choice.

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