Diethyl (Bromodifluoromethyl)phosphonate CAS 65094-22-6 Purity >97.0% (GC)

Short Description:

Chemical Name: Diethyl (Bromodifluoromethyl)phosphonate

CAS: 65094-22-6

Purity : >97.0% (GC)

Appearance: Colorless to Pale Yellow Liquid

E-Mail: alvin@ruifuchem.com

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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Diethyl (Bromodifluoromethyl)phosphonate (CAS: 65094-22-6) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	Diethyl (Bromodifluoromethyl)phosphonate
Synonyms	(Bromodifluoromethyl)phosphonic Acid Diethyl Ester
CAS Number	65094-22-6
CAT Number	RF-PI2211
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C5H10BrF2O3P
Molecular Weight	267.01
Boiling Point	102℃/16 mmHg
Solubility	Chloroform, Ethyl Acetate
Water Solubility	Not Miscible or Difficult to Mix in Water
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Colorless to Pale Yellow Liquid
Purity / Analysis Method	>97.0% (GC)
Refractive Index n20/D	1.415~1.419
Specific Gravity (20/20℃)	1.502~1.504
Water by Karl Fischer	<0.50%
Infrared Spectrum	Conforms to Structure
Proton NMR Spectrum	Conforms to Structure
Test Standard	Enterprise Standard
Usage	Pharmaceutical Intermediates

Package & Storage:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

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Application:

Diethyl (Bromodifluoromethyl)phosphonate (CAS: 65094-22-6), Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis. Diethyl (Bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.