DBU CAS 6674-22-2 1,8-Diazabicyclo[5.4.0]undec-7-ene Purity >99.0% (GC) Factory

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) (CAS: 6674-22-2) is a bicyclic amidine base. It is non-nucleophilic, sterically hindered, tertiary amine base in organic chemistry. It is reported to be superior to amine catalyst in Baylis-Hillman reaction.It promotes the methylation reaction of phenols, indoles and benzimidazoles with dimethyl carbonate under mild conditions.
DBU may be used:
1. DBU is a strong amidinebase. Serving as a proton scavenger DBU is mainly applied as a non-nucleophilic base in the synthesis of many active pharmaceutical ingredients.
2. DBU is used in organic synthesis as a catalyst, a complexing ligand, and a non-nucleophilic base. It is used as a protecting agent for the synthesis of cephalosporin and as a catalyst for polyurethane.
3. As catalyst for carboxylic acid esterification with dimethyl carbonate
4. DBU is used as a resin curing accelerator (especially for the outer cover of integrated circuits and electronic components).
5. As catalyst in aza-Michael addition and Knovenegal condensation reaction
6. DBU is used as a catalyst in the polyurethane industry. It is a highly active, low-odor gel catalyst. DBU is mainly used in catalytic situations where strong gels are required, including formulations containing ester cycloisocyanates or aliphatic isocyanates, which require strong catalysts because they are less active than aromatic isocyanates.
7. DBU is used for synthesis of heterocycle and important intermediate of medicine and pesticide or organic synthesis of block.
8. May be used as an catalyst for the dissolution and activation of cellulose by a reversible reaction of its hydroxyl groups with carbon dioxide. This dissolved cellulose system can be derivatized to form cellulose mixed esters.
9. DBU is used in the manufacture of cephalosporin semi-synthetic antibiotic drugs, and also used in the preparation of deacidification agents, rust inhibitors, advanced corrosion inhibitors, etc.