Choline Glycerophosphate CAS 28319-77-9 Assay 98.5~100.0%

Short Description:

Chemical Name: Choline Glycerophosphate

Synonyms: Alpha GPC; Choline Alfoscerate; L-α-GPC 

CAS: 28319-77-9

Assay: 98.5~100.0% (Titration)

White Powder, Neutral Odor, Very Highly Hygroscopic 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401


Product Detail

Related Products

Product Tags

28319-77-9 - Description:

Ruifu Chemical is the leading manufacturer of Choline Glycerophosphate (Alpha GPC; Choline Alfoscerate; L-α-GPC) (CAS: 28319-77-9) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Choline Glycerophosphate, Please contact:

28319-77-9 - Chemical Properties:

Chemical Name Choline Glycerophosphate 
Synonyms Alpha GPC; L-α-Glycerophosphorylcholine; Choline Alfoscerate; L-α-GPC; sn-Glycero-3-Phosphocholine; sn-Glycerophosphorylcholine; sn-Glycero-3-PC; L-α-Lecithin; L-α-Glycerylphosphorylcholine; Glycerophosphocholine
Stock Status In Stock, Production Capacity 10~12 Tons per Month  
CAS Number 28319-77-9
Molecular Formula C8H20NO6P
Molecular Weight 257.22 g/mol
Melting Point 142.5.0~143.0℃ 
Water Solubility  Soluble in Water, 1000g/L at 25℃
Stability Very Highly Hygroscopic
Sensitive Easily Absorbing Moisture
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

28319-77-9 - Specifications:

Items Specifications  Results Method
Appearance White Powder, Neutral Odor,Very Highly Hygroscopic Conforms Organoleptic
Identification  Conforms to the Standard  Conforms  TLC
Color of Solution ≤Y7  Y6  USP
Water by K.F ≤2.00%  0.70% USP
Specific Rotation   -2.4° to -2.8° -2.5°  USP
pH  4.5~6.5  5.34  USP
Releated Substance Single Spot Conforms
Assay  98.5~100.0%  99.30% Titration
Residual Solvent  Ethanol ≤0.10% Conforms GC
Heavy Metals (Pb) ≤10ppm <10ppm CPh
Arsenic (As2O3) ≤1ppm <1ppm CPh
Iron (Fe) ≤10ppm <10ppm CPh
Particle Size  80% Through 20 Mesh  Conforms USP
Conclusion  The product has been tested and complies with the given specifications


Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 


Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system


How to Purchase? Please contact Dr. Alvin Huang: or 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

28319-77-9 - Risk and Safety:

Risk Codes R11 - Highly Flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
R39/23/24/25 -
Safety Description S16 - Keep away from sources of ignition.
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S24/25 - Avoid contact with skin and eyes.
UN IDs UN 1230 3/PG 2
WGK Germany 2
RTECS KH2775000
HS Code 2923100000

28319-77-9 - Application:

Choline Glycerophosphate (Alpha GPC; Choline Alfoscerate; L-α-GPC) (CAS: 28319-77-9) can be miscible with water, soluble in methanol, ethanol, insoluble in chloroform, ether, oil, no characteristic absorption in UV-visible light.
Alpha GPC is a very effective choline source and a potent nootropic supplement. Choline is a natural precursor to the Acetylcholine neurotransmitter. Acetylcholine is responsible in learning and memory as well as other important cognitive functions. Alpha GPC works great as a supplement by itself or when stacked with racetams or other nootropics. It has also been evaluated as a possible treatment for cogntive diseases like Alzheimer's and has shown possible results in trials.
Alpha GPC is a highly concentrated version of soy lecithin that works as an effective Acetylcholine precursor. Alpha GPC is a cholinergic supplement that increases the availability of the nutrient choline in the brain. This leads to increased synthesis of the neurotransmitter acetylcholine which is implicated in memory, focus, reasoning and learning. It has received Generally Recognized As Safe (GRAS) status from the FDA and is available without a prescription in most countries.
Alpha GPC, a key brain cell membrane phospholipid and cholinergic precursor. It is a source of choline for the synthesis of the neurotransmitter acetylcholine, with a greater ability to penetrate the blood-brain barrier than conventional choline sources.
Alpha GPC has been listed in Italy, Poland, Greece, Chile, South Korea, Brazil, Russia and other countries. It not only provides the high levels of choline required by brain cells and nerve cells, but also protects their cell walls. Patients with Alzheimer's disease mainly show memory and cognitive function decline, and accompanied by a variety of complications, such as mobility inconvenience, nervous system disorders and other functional disorders. The results of clinical pharmacological tests and clinical trials have confirmed that glycerophosphorylcholine is of great help to the cognitive ability and memory function of the brain.
In Europe Alpha GPC is a prescription medication for the treatment of Alzheimer s disease. It is available in two forms; one is taken by mouth, and the other is given as a shot. In the United States alpha-GPC is only available as a dietary supplement, mostly in products promoted to improve memory.Other uses for alpha-GPC include treatment of various kinds of dementia, stroke, and "mini stroke" (transient ischemic attack, TIA). Alpha-GPC is also used for improving memory, thinking skills, and learning.  

28319-77-9 - Function & Application:

Alpha GPC Help brain recovery following injury, coma, and surgery.
Alpha GPC Improve memory and cognitive performance in patients with Alzheimer's dementia.
Alpha GPC Improve memory and learning ability.
Alpha GPC Counter the age-related loss of nerve cells and fibers in the brain.
Alpha GPC Protect the brain and other organs against toxic waste buildup.
Alpha GPC Support patients recovering from cerebral ischemic attacks.

Alpha GPC used in food additives.
Alpha GPC used in cosmetics.
Alpha GPC used in medicine.
Alpha GPC used in health-care product.  

28319-77-9 - Quality Control:

Shanghai Ruifu Chemical Co., Ltd. has advanced precision instruments and equipment ,so Ruifu Chemical can independently control product content, pesticide residue, physical and chemical properties, microorganisms, heavy metals and other quality indicators. Ruifu Chemical's goal is zero complaints.

  • Write your message here and send it to us