Paliperidone Intermediate CAS 130049-82-0 Purity >99.0% (HPLC)

Short Description:

Chemical Name: 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a]pyrimidin-4-one 

CAS: 130049-82-0

Purity: >99.0% (HPLC)

Appearance: White or Off-White Crystalline Powder

Intermediate of Paliperidone (CAS: 144598-75-4)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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130049-82-0 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a]pyrimidin-4-one (CAS: 130049-82-0) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Paliperidone Intermediates, Please contact: alvin@ruifuchem.com

Intermediates of Paliperidone:

130049-82-0 - Chemical Properties:

Chemical Name 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a]pyrimidin-4-one 
Synonyms Paliperidone Intermediate; 3-(2-Chloroethyl)-9-Hydroxy-2-Methyl-6,7,8,9-Tetrahydro-4H-Pyrido[1,2-a]pyrimidin-4-one
Impurity  Paliperidone USP Related Compound C
Stock Status In Stock, Commercial Production  
CAS Number 130049-82-0 
Molecular Formula C11H15ClN2O2
Molecular Weight 242.7 
Melting Point 101.0~109.0℃ 
Density 1.41±0.10g/cm3 
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

130049-82-0 - Specifications:

Items Specifications Results
Appearance White or Off-White Crystalline Powder Complies                   
Clarity of Solution Solution Should be Clarity Clarity
Loss on Drying <0.50% 0.31%
Residue on Ignition <0.50% 0.05%
Total Impurities <1.00% 0.50%
Purity / Analysis Method >99.0% (HPLC) 99.5%
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Paliperidone (CAS: 144598-75-4)

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

130049-82-0 - Application:

3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a]pyrimidin-4-one (CAS: 130049-82-0) is used as an Intermediate of Paliperidone (CAS: 144598-75-4). Paliperidone is FDA-approved for schizophrenia aged 12–17. However, the pharmacologic portfolio, extrapolation from adult studies, and the long track record of the parent drug, risperidone in child/adolescent psychiatric (CAP) population might expand its therapeutic potential. Paliperidone is an atypical antipsychotic. Chemically, paliperidone is the primary active metabolite of the older atypical antipsychotic risperidone. It is indicated for the acute and maintenance treatment of schizophrenia.

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