7-Aminodeacetoxycephalosporanic Acid (7-ADCA) CAS 22252-43-3; 26395-99-3 Cephalosporins Intermediate

Short Description:

7-Aminodeacetoxycephalosporanic Acid

Synonyms: 7-ADCA

CAS: 22252-43-3; 127431-38-3; 26395-99-3

Purity: ≥98.5% (on the Dried Basis)

Appearance: White or Almost White Powder

Key Intermediate in the Synthesis of Cephalosporins

Contact: Dr. Alvin Huang

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Product Detail

Product Tags

Description:

Ruifu Chemical is the leading supplier of 7-Aminodeacetoxycephalosporanic Acid (7-ADCA) (CAS: 22252-43-3; 127431-38-3; 26395-99-3) with high quality. 7-ADCA is a key intermediate in cephalosporin synthesis.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase 7-ADCA, please contact us by e-mail: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	7-Aminodeacetoxycephalosporanic Acid
Synonyms	7-ADCA; 7-Amino-3-Methyl-3-Cephem-4-Carboxylic Acid; Cephalexine EP Impurity B
CAS Number	22252-43-3; 127431-38-3; 26395-99-3
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C8H10N2O3S
Molecular Weight	214.24
Melting Point	232.0 to 234.0℃
Density	1.59±0.10 g/cm3
Stability	Stable. Incompatible with Strong Oxidizing Agents.
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	Pharmaceutical Intermediates
Brand	Ruifu Chemical

Specifications:

Item	Specifications	Results
Appearance	White or Almost White Powder	Conforms
Purity	≥98.5% (on the Dried Basis)	99.1%
Specific Rotation	+150.0°～+170.0°	+161.2°
Loss on Drying	≤0.50%	0.16%
δ-2-7-ADCA	≤0.50%	0.31%
Color	≤0.20% (425nm absorption)	0.075%
Test Standard	Enterprise Standard	Conforms
Usage	Key Intermediate in the Synthesis of Cephalosporins

Package/Storage/Shipping:

Package: Fluorinated bottle, aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry and well-ventilated warehouse away from incompatible substances. Keep away from direct sunlight; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

FAQ:

Risk and Safety:

Hazard Symbols Xn - Harmful
Risk Codes
R42/43 - May cause sensitization by inhalation and skin contact.
R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
HS Code 2941901010

Application:

7-Aminodeacetoxycephalosporanic Acid (7-ADCA) (CAS: 22252-43-3; 127431-38-3; 26395-99-3), a cephem monocarboxylic acid derivative having a structure based on cephalosporanic acid, deacetoxylated and carrying a 7beta-amino group. 7-ADCA is a key intermediate in the synthesis of cephalosporins, is an antibiotic core, used as a pharmaceutical intermediate.
7-ADCA is used for the synthesis of Cephalexin (CAS: 15686-71-2), Cefadroxil (CAS: 66592-87-8), Cephradine (CAS: 38821-53-3), Cefuroxime Sodium (CAS: 56238-63-2) and Cefetamet Esters.
7-ADCA is the Cephalexin metabolite. It is a Potent inhibitor of bacterial cell-wall enzyme. It is used in the synthesis of cephalosporins and for bioconversion studies.