3-HydroxyCephem (3-OH) CAS 54639-48-4 Purity ≥99.0% (HPLC) Cephalosporin Ceftaroline Fosamil Intermediate

Short Description:

Name: 3-HydroxyCephem (3-OH)

CAS: 54639-48-4

Purity: ≥99.0% (HPLC)

Appearance: White or Off-White Powder

Intermediate for Cephalosporins, Ceftaroline Fosamil

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Manufacturer Supply, High Purity, Commercial Production
Chemical Name: 3-HydroxyCephem (3-OH)
CAS: 54639-48-4

Chemical Properties:

Chemical Name	(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester
Synonyms	3-HydroxyCephem; 3-OH; GHYH
CAS Number	54639-48-4
CAT Number	RF-PI560
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C28H24N2O5S
Molecular Weight	500.57
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White or Off-White Powder
Identification	IR, NMR Positive
Purity / Analysis Method	≥99.0% (HPLC)
Moisture (K.F)	≤0.50%
Single Impurity	≤0.50%
Total Impurities	≤1.0%
Residual Solvents	≤1.0%
Penicillin Potassium Residual	≤1ppm
Test Standard	Enterprise Standard
Usage	Intermediate for Cephalosporins-derived inhibitors, Ceftaroline Fosamil

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

FAQ:

Application:

3-Hydroxycephem (3-OH) (CAS: 54639-48-4), main chain of Cephalosporin, is used to prepare Cephalosporin-derived inhibitors. It can also be used to synthesize Ceftaroline Fosamil which is a Cephalosporin antibiotic. Ceftaroline, the active metabolite of the prodrug Ceftaroline Fosamil (Zinforo, Teflaro), is an advanced-generation, parenteral Cephalosporin with broad-spectrum antibacterial activity in vitro against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug resistant Streptococcus pneumoniae and Gram-negative bacteria, including Haemophilus influenzae and Moraxella catarrhalis, but not Pseudomonas aeruginosa.