6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9 PF-07321332 Boceprevir Intermediate

Short Description:


CAS: 943516-54-9

Appearance: Colorless Transparent Liquid

Purity: ≥98.0% (GC)

Intermediate of PF-07321332 Paxlovid (CAS 2628280-40-8) and Boceprevir (CAS 394730-60-0)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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943516-54-9 - Chemical Properties:

Chemical Name 6,6-Dimethyl-3-azabicyclo[3.1.0]hexane
CAS Number 943516-54-9
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C7H13N
Molecular Weight 111.18
Boiling Point 135℃
Density  0.911
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories Pharmaceutical Intermediates
Brand Ruifu Chemical

943516-54-9 - Specifications:

Item Specifications
Appearance Colorless Transparent Liquid
Purity ≥98.0% (GC)
Total Impurities ≤2.00%
Heavy Metals  ≤20ppm
NMR Spectrum 1H  Conforms to Structure
Test Standard Enterprise Standard
Usage: Intermediate of PF-07321332 Paxlovid (CAS 2628280-40-8) and Boceprevir (CAS 394730-60-0)

943516-54-9 - Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

943516-54-9 - Advantages:


943516-54-9 - FAQ:


943516-54-9 - Application:

6,6-Dimethyl-3-azabicyclo[3.1.0]hexane (CAS 943516-54-9) is the intermediate of PF-07321332 Paxlovid (CAS 2628280-40-8) and Boceprevir (CAS 394730-60-0). Pfizer's Paxlovid PF-07321332 is an oral antiviral therapeutic targeting the SARS-CoV-2 betacoronavirus to prevent COVID-19. Paxlovid is a protease inhibitor that has demonstrated potent in vitro antiviral activity against SARS-CoV-2 and other coronaviruses, suggesting potential for use in the treatment of COVID-19, as well as potential use against future virus threats, says Pfizer. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay. Boceprevir inhibits SARS-CoV-2 3CLpro activity.

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