L-tert-Leucine (H-Tle-OH) CAS 20859-02-3 Assay 98.0%~102.0%

Short Description:

Chemical Name: L-tert-Leucine  

Synonyms: H-Tle-OH 

CAS: 20859-02-3

Appearance: White to Off-White Powder

Assay: 98.0%~102.0% (on Dried Basis) 

Contact: Dr. Alvin Huang     

Mobile/Wechat/WhatsApp: +86-15026746401 

Inquiry: alvin@ruifuchem.com

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20859-02-3 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of L-tert-Leucine (H-Tle-OH) (CAS: 20859-02-3 ) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase L-tert-Leucine, Please contact: alvin@ruifuchem.com 

20859-02-3 - Chemical Properties:

Chemical Name L-tert-Leucine  
Synonyms H-Tle-OH; (S)-2-Amino-3,3-Dimethylbutyric Acid; (S)-2-amino-3,3-Dimethylbutanoic Acid
CAS Number 20859-02-3
Stock Status In Stock, Production Scale Up to 120 Tons/Month
Molecular Formula C6H13NO2
Molecular Weight 131.17
Melting Point ≥300.0℃(lit.)
Density 1.0±0.1 g/cm3
Water Solubility Soluble in Water 
Storage  Store at Room Temperature
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories Amino Acid; Pharmaceutical Intermediate
Brand Ruifu Chemical

20859-02-3 - Specifications:

Item Specifications Results
Appearance White to Off-White Powder White Powder               
Identification IR; HPLC Conforms  
Solubility Soluble in Water Conforms 
Loss on Drying ≤0.50% 0.23% 
Residue on Ignition              ≤0.20% 0.06% 
Specific Rotation -8.0°~ -11.0° (C=3% in Water) -9.1° 
Heavy Metals (Pb) ≤10ppm <10ppm
Related Substances    
Enantiomeric Purity D-Ter-Leucine ≤0.50% <0.50% 
Any Other Impurity ≤0.50% <0.50% 
Total Impurities ≤1.00% <1.00% 
L-tert-Leucine Assay 98.0%~102.0% (on Dried Basis) 99.7% 
Conclusion The product has been tested and complies with the given specifications 

20859-02-3 - Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Preserve in well sealed container, store in cool and dried place, away from strong light and heat, when stored under above condition, the retested date is 2 years away from manufactured date.

20859-02-3 - Advantages:


20859-02-3 - FAQ:


20859-02-3 - Risk and Safety:

Hazard Symbols Xi - Irritant
Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 3
RTECS OH2850000
HS Code 2922491990
Hazard Note Irritant

20859-02-3 - Application:

H-Tle-OH, L-tert-Leucine (CAS 20859-02-3) is an essential amino acid making up one third of our muscle protein. L-tert-leucine is important in developing chiral pharmaceutically active chemicals. It can also be used for the production of Chiral tridentate Schiff base ligands. It is a nonproteogen chiral amino acid. Because of the high steric hindrance of tert-butyl group, the derivatives of tert-leucine can be used as templates to induce asymmetry in asymmetric synthesis.  Because of the large tert-butyl chain and its hydrophobicity, it can well control the molecular conformation in the synthesis of polypeptides, and increase the hydrophobicity of polypeptides and the stability of enzymatic degradation.  Our company produces L-tert-leucine by enzymatic process, the reaction conditions are mild, not easy to cause environmental pollution. It can be used as a Nutritional Supplements, Food and Feed Additives; it can be used for synthetic Anti-AIDs drugs (Atazanavir Sulfate) and Anti-HCV drugs (Telaprevir) and etc. L-tert-Leucine (CAS 20859-02-3) also can be used in the peptide synthesis.

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