5-Cyanoindole CAS 15861-24-2 Purity >99.0% (HPLC) Factory

Short Description:

Chemical Name: 5-Cyanoindole

CAS: 15861-24-2

Purity: >99.0% (HPLC)

Appearance: Pale Yellow Crystalline Powder

Intermediate of API (CAS: 163521-08-2)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Chemical Name 5-Cyanoindole
Synonyms 5-Cyano-1H-Indole; Indoline-5-Carbonitrile; 1H-Indole-5-Carbonitrile
CAS Number 15861-24-2
CAT Number RF-PI1493
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C9H6N2
Molecular Weight 142.16
Melting Point 106.0~108.0℃ (lit.)
Solubility  Soluble in Chloroform, Hexane and Methanol. Insoluble in Water
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Pale Yellow Crystalline Powder
Identification The retention time of the major peak in the chromatogram of the sample corresponds to that in the chromatogram obtained with the standard
Purity / Analysis Method >99.0% (HPLC)
Loss on Drying ≤0.20%(At 105°C for 3.0 hrs.)
Water Content ≤0.20%
Residue on Ignition ≤0.20%
Single Impurity ≤0.50%
Total Impurities <1.00%
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates; Intermediate of API (CAS: 163521-08-2)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

5-Cyanoindole (CAS: 15861-24-2) is mainly used in pharmaceutical industry as a pharmaceutical intermediate. 5-Cyanoindole can be used as an intermediate of API (CAS: 163521-08-2), which is a kind of serotonergic antidepressant developed by Merck KGaA Company. API (CAS: 163521-08-2) is a novel compound with high affinity and selectivity for the 5-hydroxytrptamine (5-HT) transporter and 5-HT (1A) receptors, it is indicated for the treatment of major depressive disorder (MDD), it is can be used as an alternative drugs for other kind of antidepressant classes drugs that can’t be tolerated by patients. As a selective serotonin reuptake inhibitor, (CAS: 163521-08-2) can prevent the serotonin from re-entering into cell bodies, therefore making it remain longer inside the synapse. Moreover, (CAS: 163521-08-2) has a high selectivity for the serotonin-1A receptor, taking effect as a partial agonist that can simulate the production of serotonin. These effects result in increased serotonin in the synaptic cleft. This effect is related to the antidepressant effect of it in vivo.

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