3-(4-Chlorobutyl)-5-Cyanoindole CAS 143612-79-7 Purity >99.0% (HPLC) Factory

Short Description:

Chemical Name: 3-(4-Chlorobutyl)-5-Cyanoindole

CAS: 143612-79-7

Purity: >99.0% (HPLC)

Appearance: Off-White to Light Yellow Powder

Intermediate of API (CAS: 163521-08-2)  

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Chemical Name 3-(4-Chlorobutyl)-5-Cyanoindole
Synonyms 3-(4-Chlorobutyl)-1H-Indole-5-Carbonitrile; 3-(4-Chlorobutyl)indole-5-Carbonitrile 
CAS Number 143612-79-7
CAT Number RF-PI1494
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C13H13ClN2
Molecular Weight 232.71
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Off-White to Light Yellow Powder
Purity / Analysis Method >99.0% (HPLC)
Melting Point 98.0~102.0℃
Moisture (K.F) ≤0.50%
Single Impurity ≤0.50%
Total Impurities <1.00%
Test Standard Enterprise Standard
Usage Intermediate of API (CAS: 163521-08-2)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

3-(4-Chlorobutyl)-5-Cyanoindole (CAS: 143612-79-7) can be obtained by acylation reaction and reduction reaction of 5-Cyanoindole (CAS: 15861-24-2) and 4-Chlorobutyryl Chloride (CAS: 4635-59-0). 3-(4-Chlorobutyl)-5-Cyanoindole is a key intermediate in the synthesis of API (CAS: 163521-08-2). In January 2011, the U.S. FDA approved (CAS: 163521-08-2) for the treatment of major depressive disorder (MDD). (CAS: 163521-08-2) is a novel antidepressant agent that combines potent serotonin reuptake inhibition (IC50=0.2 nM) with high affinity for 5-HT1A receptors (IC50=0.5 nM)and partial 5-HT1A receptor agonist functional activity. (CAS: 163521-08-2) has good selectivity over other monoamine receptors.

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