4-Chlorobutyryl Chloride CAS 4635-59-0 Purity >99.0% (GC) Levetiracetam Intermediate

Short Description:

Chemical Name: 4-Chlorobutyryl Chloride 

CAS: 4635-59-0

Purity: >99.0% (GC)

Appearance: Colorless to Light Yellow Clear Liquid 

Intermediate of Levetiracetam (CAS: 102767-28-2)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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4635-59-0 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 4-Chlorobutyryl Chloride (4-CBC) (CAS: 4635-59-0) with high quality, intermediate of Levetiracetam (CAS: 102767-28-2). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 4-Chlorobutyryl Chloride, Please contact: alvin@ruifuchem.com

Intermediates of Levetiracetam:

4635-59-0 - Chemical Properties:

Chemical Name 4-Chlorobutyryl Chloride 
Synonyms 4-CBC; 4-CBCl; 4-Chlorobutanoic Acid Chloride; 4-Chlorobutanoyl Chloride; 4-Chlorobutyric Acid Chloride; 4-Chlorobutyroyl Chloride; γ-Chlorobutyroyl Chloride; γ-Chlorobutyryl Chloride; ω-Chlorobutanoyl Chloride; ω-Chlorobutyryl Chloride
Stock Status In Stock, Production Capacity 600 Tons per Year
CAS Number 4635-59-0
Molecular Formula C4H6Cl2O
Molecular Weight 140.99 g/mol
Melting Point -47.0℃(lit.) 
Boiling Point 173.0~174.0℃(lit.) 
Flash Point 163°F  
Density 1.260 g/mL at 25℃(lit.) 
Refractive Index n20/D 1.461(lit.)
Store Under Inert Gas Store Under Inert Gas
Sensitive Moisture Sensitive. Ambient Temperatures
Solubility  Soluble in Diethyl Ether, Ethanol; Slightly Soluble in Water 
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical

4635-59-0 - Specifications:

Items Specifications  Results
Appearance Colorless to Light Yellow Clear Liquid   Complies 
Water by Karl Fischer  <0.20% 0.09%
Refractive Index n20/D 1.460~1.464 Complies             
Density (20℃) 1.256~1.263 Complies
4-Chlorobutyryl Chloride Purity >99.0% (GC) 99.5%
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Levetiracetam (CAS: 102767-28-2)

4635-59-0 - Package/Storage/Shipping:

Package: Fluorinated Bottle, 25kg/Drum, 200kg/Drum, or according to customer's requirement.
Storage Condition: Moisture sensitive. Store under inert gas. Keep the container tightly closed and store in a cool, dry, well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Store away from oxidizing agent, bases.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

4635-59-0 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

4635-59-0 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

4635-59-0 - Risk and Safety:

Risk Codes R22 - Harmful if swallowed
R23 - Toxic by inhalation
R35 - Causes severe burns
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S28A -
UN IDs UN 3390 6.1/PG 1
WGK Germany 1
RTECS EM1406000
HS Code 2942000000
Hazard Note Toxic/Corrosive/Moisture Sensitive
Hazard Class 6.1
Packing Group II

4635-59-0 - Application:

4-Chlorobutyryl Chloride (4-CBC) (CAS: 4635-59-0) is a colorless to light yellow clear liquid with a pungent odor. It is a chlorinated derivative of butyric acid.
4-Chlorobutyryl Chloride is mainly used in the production of pharmaceuticals, agrochemicals and other organic compounds. It is also used as a reagent in the preparation of various derivatives of butyric acid.
4-Chlorobutyryl Chloride can be used as a pharmaceutical intermediate in the synthesis of Levetiracetam (CAS: 102767-28-2). Levetiracetam can be prepared by condensation of (S)-2-Aminobutyramide Hydrochloride (CAS 7682-20-4) with 4-Chlorobutyryl Chloride. Levetiracetam is a third-generation antiepileptic drug, used as adjunctive therapy in the treatment of partial onset seizures in adults and children 4 years of age and older with epilepsy. 

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