Trimethyl Orthoformate (TMOF) CAS 149-73-5 Purity >99.5% (GC) Azoxystrobin Intermediate

Short Description:

Chemical Name: Trimethyl Orthoformate

Synonyms: TMOF; Trimethoxymethane 

CAS: 149-73-5

Purity: >99.5% (GC)

Appearance: Colorless Clear Liquid 

Production Capacity 5000 Metric Tons per Year 

Intermediate of Azoxystrobin (CAS: 131860-33-8)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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149-73-5 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Trimethyl Orthoformate (TMOF) (CAS: 149-73-5) with high quality, production capacity 5000 metric tons per year. In the pesticide industry, Trimethyl Orthoformate is mainly used in the synthesis of Azoxystrobin (CAS: 131860-33-8), and other pesticides or pharmaceuticals intermediates. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Trimethyl Orthoformate, Please contact: alvin@ruifuchem.com

Intermediates of Azoxystrobin:

149-73-5 - Chemical Properties:

Chemical Name Trimethyl Orthoformate  
Synonyms TMOF; Trimethoxymethane; Methyl Orthoformate; Orthoformic Acid Trimethyl Ester; Perma-Flo OF
Stock Status In Stock, Production Capacity 5000 Tons per Year
CAS Number 149-73-5
Molecular Formula C4H10O3 
Molecular Weight 106.12 g/mol
Melting Point -53℃ 
Boiling Point 100℃
Flash Point 15℃
Specific Gravity (20/20)    0.97 
Refractive Index n20/D 1.38
Sensitive Moisture Sensitive. Store Under Inert Gas
Solubility  Soluble in Ether, Benzene, Alcohol
COA & MSDS Available
Sample  Available
Origin China
Brand Ruifu Chemical

149-73-5 - Specifications:

Items Specifications  Results
Appearance Colorless Clear Liquid   Colorless Clear Liquid    
Trimethyl Orthoformate   >99.5% (GC) 99.63%
Water by Karl Fischer  <0.05% 0.026% 
Density (20℃) 0.968~0.972 Complies 
Refractive Index n20/D  1.377~1.380 Complies 
Methyl Formate <0.20% 0.042%
Methanol <0.20% 0.012%
Triazine <0.02% <0.02%
Free Acid (as Formic Acid) <0.05% <0.05%
Other Individual Impurity <0.10% <0.10%
Color (APHA) <20 10
Infrared Spectrum Consistent with Structure Complies 
Conclusion The product has been tested and complies with the given specifications

149-73-5 - Package/Storage/Shipping:

Package: Fluorinated Bottle, plastic drum or galvanized iron drum, net weight 200kgs per drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Away from fire and open flame; Store and transport Isolation with oxidant to avoid sun exposure.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

149-73-5 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

149-73-5 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

149-73-5 - Risk and Safety:

Risk Codes R11 - Highly Flammable
R36 - Irritating to the eyes
Safety Description S9 - Keep container in a well-ventilated place.
S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S29 - Do not empty into drains.
UN IDs UN 3272 3/PG 2
WGK Germany 1
RTECS RM6650000
TSCA Yes
HS Code 2942000000
Hazard Class 3
Packing Group II

149-73-5 - Application:

Trimethyl Orthoformate (TMOF) (CAS: 149-73-5) is used as an organic synthesis intermediate, pesticide intermediate, pharmaceutical intermediate.
Trimethyl Orthoformate is a highly reactive compound that can be used in a variety of reactions, including acylation, alkylation, and condensation reactions. It is commonly used as a protecting group for aldehydes and ketones, and as a source of methyl groups in reactions that require them.
In the pesticide industry, Trimethyl Orthoformate is mainly used in the synthesis of Azoxystrobin (CAS: 131860-33-8), and other pesticide intermediates. Azoxystrobin is a methoxyacrylate fungicidal pesticide, highly efficient and broad-spectrum, with good activity against almost all diseases of the fungal kingdom (subphylum Cysticerca, subphylum Streptomyces, subphylum Flagellum and subphylum Hemiptera) such as powdery mildew, rust, glume blight, reticulosis, downy mildew, rice blast, etc. It can be used for stem and leaf spray, seed treatment, and also soil treatment, mainly for cereals, rice, peanuts, grapes, potatoes, fruit trees, vegetables, coffee, lawns, etc.
Trimethyl Orthoformate is also used as an intermediate for the production of vitamin B1, sulfanilamide drugs, antibiotics and other drugs, and is also a raw material for spices and an additive for polyurethane coatings.
However, Trimethyl Orthoformate is also highly flammable and can be dangerous if not handled properly. It is important to follow proper safety procedures when working with this compound, such as wearing protective clothing and working in a well-ventilated area. 

149-73-5 - Caution:

Trimethyl Orthoformate (TMOF) (CAS: 149-73-5) is also highly flammable and can be dangerous if not handled properly. It is important to follow proper safety procedures when working with this compound, such as wearing protective clothing and working in a well-ventilated area. 

149-73-5 - Safety Profile:

A skin and eye irritant. A very dangerous fire hazard when exposed to heat or flame; can react with oxidizing materials. Hazardous to prepare. To fight fire, use CO2, fog, haze. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.   

149-73-5 - Flammability:

Flammability hazard characteristics: In case of open flame, high temperature, flammable oxidant; Combustion stimulus smoke.
Extinguishing agent: Dry powder, dry sand, carbon dioxide, foam, 1211 extinguishing agent.

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