Tosylmethyl Isocyanide (TosMIC) CAS 36635-61-7 Purity >99.0% (HPLC)

Short Description:

p-Toluenesulfonylmethyl Isocyanide

Synonyms: TosMIC; Tosylmethyl Isocyanide 

CAS: 36635-61-7

Purity: >99.0% (HPLC)

Light Yellow to Light Brown Crystalline Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of p-Toluenesulfonylmethyl Isocyanide (TosMIC; Tosylmethyl Isocyanide) (CAS: 36635-61-7) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase TosMIC, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name p-Toluenesulfonylmethyl Isocyanide 
Synonyms TosMIC; Tosylmethyl Isocyanide; (p-Tolylsulfonyl)methyl Isocyanide; 1-[(Isocyanomethyl)sulfonyl]-4-Methylbenzene; p-Toluenesulfonylmethyl Isocyanide; p-Toluenesulfonylmethylisonitrile; p-Tosylmethyl Isocyanide; p-Tosylmethyl Isonitrile
Stock Status In Stock, Commercially Manufactured
CAS Number 36635-61-7
Molecular Formula C9H9NO2S
Molecular Weight 195.24 g/mol
Melting Point 108.0~115.0℃ 
Sensitive Moisture, Heat, Air and Light Sensitive
Solubility  Soluble in Chloroform and Methanol. Insoluble in Water
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance Light Yellow to Light Brown Crystalline Powder Complies      
Melting Point 108.0~115.0℃ 110.0~112.0℃
Loss on Drying <0.50% 0.15% 
Residue on Ignition <0.20% 0.08%
Heavy Metals (Pb) ≤20ppm <20ppm
Purity / Analysis Method >99.0% (HPLC)  99.5% 
Purity (Titration)  97.5~102.5% Complies      
Infrared Spectrum Conforms to Structure Complies      
NMR Spectrum  Conforms to Structure Complies      
Conclusion The product has been tested & complies with the given specifications

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Moisture, heat, air and light sensitive. Store in a tightly closed container. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Incompatible with strong bases and strong oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

36635-61-7 - Risk and Safety:

Risk Codes
23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
Safety Description
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S38 - In case of insufficient ventilation, wear suitable respiratory equipment.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S28A -
UN IDs UN 2811 6.1/PG 3
WGK Germany 3
FLUKA BRAND F CODES 21
HS Code 2935900090
Hazard Note Irritant
Hazard Class 6.1(b)
Packing Group III

Application:

p-Toluenesulfonylmethyl Isocyanide (TosMIC; Tosylmethyl Isocyanide) (CAS: 36635-61-7) is used as an organic synthesis intermediate, pharmaceutical intermediate, pesticide intermediate, or chemical reagent.
Tosylmethyl Isocyanide is used as a synthetic reagent in the preparation of variety or biologically active heterocycles such as pyrroles and imidazoles. As isonitrile components, used in stereoselective Passerini reactions containing carbohydrate-derived aldehydes.
Versatile synthon in organic chemistry, especially in the synthesis of heterocyclic compounds.
Tosylmethyl Isocyanide contains both sulfonyl and isocyanide groups. Unlike many isocyanides, it is odorless. It is prepared by dehydration of the related formamide derivative. It is used in the Van Leusen reaction which is used to convert aldehydes to nitriles or in the preparation of oxazoles and imidazoles. 

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