tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 Purity >98.0% (HPLC) Palbociclib Intermediate Factory

Short Description:

Chemical Name: tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate

Synonyms: 1-Boc-4-(6-Nitro-3-Pyridyl)piperazine

CAS: 571189-16-7

Purity: >98.0% (HPLC)

Appearance: Light Brown to Brown Powder

Intermediate of Palbociclib (CAS: 571190-30-2)

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Product Detail

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Description:

Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Chemical Properties:

Chemical Name	tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate
Synonyms	1-Boc-4-(6-Nitro-3-Pyridyl)piperazine; 4-(6-Nitro-3-pyridinyl)-1-Piperazinecarboxylic Acid tert-Butyl Ester; tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate
CAS Number	571189-16-7
CAT Number	RF-PI1850
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C14H20N4O4
Molecular Weight	308.33
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Light Brown to Brown Powder
Purity / Analysis Method	>98.0% (HPLC)
LCMS	Consistent With Structure
Loss on Drying	<1.00%
Total Impurities	<2.00%
Test Standard	Enterprise Standard
Usage	Intermediate of Palbociclib (CAS: 571190-30-2)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate (CAS: 571189-16-7) is an intermediate of Palbociclib (CAS: 571190-30-2). Palbociclib (also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Palbociclib blocks cell cycle progression from phase G1 into S by inhibiting CDK4/6-dependent retinoblastoma (RB) phosphorylation. Palbociclibhas been used for the treatment of HER2 negative, estrogen receptor (ER) positive metastatic breast cancer.