5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5 Purity >99.0% (GC) Palbociclib Intermediate Factory

Short Description:

Chemical Name: 5-Bromo-2,4-Dichloropyrimidine

CAS: 36082-50-5

Purity: >99.0% (GC)

Appearance: Colorless to Light Yellow Liquid

Intermediate of Palbociclib (CAS: 571190-30-2)

High Quality, Commercial Production

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Product Detail

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Description:

Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Chemical Properties:

Chemical Name	5-Bromo-2,4-Dichloropyrimidine
CAS Number	36082-50-5
CAT Number	RF-PI1852
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C4HBrCl2N2
Molecular Weight	227.87
Boiling Point	128℃/15 mmHg (lit.)
Density	1.781 g/mL at 25℃ (lit.)
Refractive Index	n20/D 1.603 (lit.)
Solubility	Soluble in Methanol
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Colorless to Light Yellow Liquid
Purity / Analysis Method	>99.0% (GC)
Melting Point	29.0~30.0℃
Water (by Karl Fischer)	<0.50%
2,4-Dichloropyrimidine	<0.50% (GC)
Maximun Single Impurity	<0.50% (GC)
Total Impurities	<1.00%
1 H NMR Spectrum	Consistent With Structure
Test Standard	Enterprise Standard
Usage	Intermediate of Palbociclib (CAS: 571190-30-2)

Package & Storage:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

5-Bromo-2,4-Dichloropyrimidine (CAS: 36082-50-5) may be employed as starting reagent for the synthesis of positive allosteric modulators for GABAB receptors (drug-like class of compounds) and pyridinepyrimidine analogs. 5-Bromo-2,4-Dichloropyrimidine can be used as an intermediate of Palbociclib (CAS: 571190-30-2). Palbociclib (also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. Palbociclib is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.