RuPhos CAS 787618-22-8 Assay ≥98.0% (HPLC) Factory

Short Description:

2-Dicyclohexylphosphino-2′,6′-Diisopropoxybiphenyl

Synonyms: RuPhos 

CAS: 787618-22-8

Assay: ≥98.0% (HPLC)

Appearance: White Powder 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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787618-22-8 - Description:

Ruifu Chemical is the leading manufacturer of 2-Dicyclohexylphosphino-2',6'-Diisopropoxybiphenyl (RuPhos) (CAS: 787618-22-8) with high quality. Ruifu can provide worldwide delivery, competitive price, excellent service.
Purchase RuPhos or other products, please contact us by e-mail: alvin@ruifuchem.com

787618-22-8 - Chemical Properties:

Chemical Name 2-Dicyclohexylphosphino-2',6'-Diisopropoxybiphenyl 
Synonyms RuPhos; Dicyclohexyl(2',6'-Diisopropoxy-[1,1'-Biphenyl]-2-yl)phosphine; 2-Dicyclohexylphosphino-2',6'-Diisopropoxy-1,1'-Biphenyl
Stock Status In Stock, Commercial Production  
CAS Number 787618-22-8
Molecular Formula C30H43O2P
Molecular Weight 466.65 g/mol
Melting Point 123.0 to 126.0℃ 
Sensitive Air Sensitive. Store Under Nitrogen. 
Solubility  Soluble in Toluene. Insoluble in Water 
Storage Temperature Store Long-Term at 2-8℃
Shipping Conditions Ambient Temperatures
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Phosphine Ligand 
Brand Ruifu Chemical

787618-22-8 - Specifications:

Items Specifications  Results
Appearance White Powder   White Powder 
Assay / Analysis Method ≥98.0% (HPLC)  98.5%
Melting Point 123.0~126.0℃  123.0~124.0℃ 
Infrared Spectrum Conforms to Structure   Conforms 
NMR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications

787618-22-8 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Air Sensitive. Store under inert gas. Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Store away from strong oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

787618-22-8 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

787618-22-8 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

787618-22-8 - Risk and Safety:

Hazard Symbols Xn - Harmful
Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany 3
TSCA No
HS Code 2931900090

787618-22-8 - Introduction:

2-Dicyclohexylphosphino-2',6'-Diisopropoxybiphenyl (RuPhos) (CAS: 787618-22-8) is a very important class of ligands which has gained great attention in modern organic chemistry, catalysis, and material science. It was first described by William R. Roush in 2002. RuPhos ligands are useful for a wide range of reactions, including Suzuki-Miyaura cross-coupling reactions, C-H activation, and allylic substitutions. They also possess unique properties, such as high solubility, stability, and ease of separation from reaction mixtures.

787618-22-8 - Definition and Background:

RuPhos (CAS: 787618-22-8) is a class of phosphorus- and ruthenium-containing ligands that have revolutionized the field of catalysis. These ligands were developed to address some of the limitations of existing palladium-based catalytic systems. RuPhos is derived from the earlier Phosphaferrocene-based ligands, which were developed by John A. Gladysz in the 1970s and 1980s.

787618-22-8 - Physical and Chemical Properties:

RuPhos ligands possess unique physical and chemical properties. They are soluble in a range of solvents, including polar and non-polar solvents. This is attributed to the presence of phosphorus and ruthenium atoms, which provide high solubility and stability. RuPhos ligands are also air-sensitive and should be stored under an inert atmosphere.

787618-22-8 - Toxicity and Safety in Scientific Experiments:

RuPhos ligands are generally considered to be safe and non-toxic to humans and animals. However, care should be taken to avoid skin and eye contact, ingestion, or inhalation of the ligands. Moreover, proper ventilation and personal protective equipment should be used when working with RuPhos ligands.   

787618-22-8 - Applications in Scientific Experiments:

RuPhos ligands have numerous applications in organic synthesis, catalysis, and material science. They are particularly useful for Suzuki-Miyaura cross-coupling reactions, which have been widely used in the synthesis of natural products, pharmaceutical intermediates, and materials. Other applications include C-H activation, allylic substitutions, and cycloaddition reactions.   

Potential Implications in Various Fields of Research & Industry:

RuPhos ligands have the potential to revolutionize various fields of research and industry. They could be used to develop new, sustainable synthetic routes for the production of chemicals, materials, and pharmaceuticals. In addition, they could be used to develop more efficient and environmentally friendly catalytic systems for industrial processes.   

787618-22-8 - Conclusion:

RuPhos ligands have revolutionized the field of catalysis since their discovery in 2002. They have unique properties that make them suitable for a wide range of reactions, and their applications are still being explored in various fields of research and industry. Although there are still challenges in developing better synthetic methods and exploring new applications, the future of RuPhos ligands is promising, and they have the potential to have a significant impact on the fields of chemistry, material science, and catalysis. 

787618-22-8 - Reaction Type:

Buchwald-Hartwig Cross Coupling Reaction
Heck Reaction
Hiyama Coupling
Negishi Coupling
Sonogashira Coupling
Stille Coupling
Suzuki-Miyaura Coupling
catalyst
Cross Couplings
Ligand

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