Pentafluorophenol CAS 771-61-9 (PFP-OH) Purity ≥99.0% (HPLC) Factory High Purity

Pentafluorophenol (CAS: 771-61-9) can be used for the preparation of penta-fluorophenyl esters for peptide synthesis. It is used in the preparation of pentafluorophenyl esters for peptide synthesis and vulcanized polymers. It is also used for peptide coupling and heterocyclic acid derivatives. It is involved in the preparation of pentafluorophenyl formate which acts as a formulating agent for amines and amino acids. It can be used for synthesizing novel reagents which can achieve highly diastereoselective acetal cleavage.
Pentafluorophenol is also the intermediate of Sofosbuvir in the treatment of Hepatitis C Virus (HCV).
Pentafluorophenol is a polyfluoro liquid crystal compound with small steric hindrance, which is an important intermediate for the preparation of high performance liquid crystal materials, it is especially suitable for the preparation of polyfluoro monomer liquid crystal materials. After the polyfluoro monomer liquid crystal materials are mixed with low viscosity and high dielectric anisotropy nematic liquid crystal materials, the dipole distance of molecules can be increased, reducing the response time, improving the display performance of the liquid crystal material, increasing the clarity, has an important meaning to the production of high performance liquid crystal materials.
Pentafluorophenol is an important intermediate, mainly used in the preparation of pharmaceutical, liquid crystal and polymer materials intermediates, such, in the field of medicine and pesticide, pentafluorophenol is used to prepare pentafluorophenyl active ester for peptide synthesis, thus promoting the formation of peptide, pentafluorophenyl ester can be used for solid phase synthesis of peptides, it can also be used for liquid phase synthesis, and can also be used as a protecting group for an amino acid protecting group alkyl ester or sulfonic acid group.