Neratinib Maleate (HKI-272 Maleate) CAS 915942-22-2 Assay ≥98.0% (HPLC)

Short Description:

Chemical Name: Neratinib Maleate

Synonyms: HKI-272 Maleate 

CAS: 915942-22-2

Neratinib CAS: 698387-09-6

Assay: ≥98.0% (HPLC)

Appearance: White to Off-White Powder 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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915942-22-2 - Description:

Ruifu Chemical is the leading supplier of Neratinib Maleate (HKI-272 Maleate) (CAS: 915942-22-2) with high quality. Ruifu has been supplying APIs (active pharmaceutical ingredients) and pharmaceutical intermediates more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Neratinib Maleate or other products, please contact us by e-mail: alvin@ruifuchem.com

915942-22-2 - Chemical Properties:

Chemical Name Neratinib Maleate
Synonyms HKI-272 Maleate; Nerlynx; (E)-N-[4-[3-Chloro-4-[(2-Pyridinyl)methoxy] anilino]-3-Cyano-7-Ethoxy-6-Quinolinyl]-4-(Dimethylamino)-2-Butenamide Maleate
Inventory In Stock
CAS Number 915942-22-2
Neratinib CAS  698387-09-6
Molecular Formula C30H29ClN6O3.C4H4O4
Molecular Weight 673.11 g/mol
Storage Temperature Store Long-Term at 2-8℃, Inert Atmosphere
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
API (Active Pharmaceutical Ingredient) 
Caution Not For Human or Veterinary Use. For Research Use Only.
Brand Ruifu Chemical

915942-22-2 - Specifications:

Items Specifications  Results
Appearance White to Off-White Powder  Conforms  
Assay / Analysis Method ≥98.0% (HPLC)  99.1%
Infrared Spectrum Conforms to Structure   Conforms 
NMR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications

915942-22-2 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

915942-22-2 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

915942-22-2 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

915942-22-2 - Safety Information:

HS Code 2933 4900.40                             

915942-22-2 - Application:

Neratinib Maleate (HKI-272 Maleate) (CAS: 915942-22-2) is an irreversible epidermal grow factor receptor (EGFR) inhibitor. Neratinib Maleate is a small molecule tyrosine kinase inhibitor targeting HER2 and HER1 after lapatinib. Neratinib Maleate is an irreversible pan erbB receptor tyrosine kinase inhibitor. It can selectively inhibit HER-1 and HER-2 (IC50 = 92 nmol / L and 59 nmol / L, respectively). Clinical studies have shown that it has obvious therapeutic effect on non-small cell lung cancer, colon cancer and breast cancer. 

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