Neratinib (HKI-272) CAS 698387-09-6 Assay ≥98.0% (HPLC)

Short Description:

Chemical Name: Neratinib

Synonyms: HKI-272 

CAS: 698387-09-6

Neratinib Maleate CAS: 915942-22-2

Assay: ≥98.0% (HPLC)

Appearance: Faint Yellow to Yellow Solid Powder 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401


Product Detail

Related Products

Product Tags

698387-09-6 - Description:

Ruifu Chemical is the leading supplier of Neratinib (HKI-272) (CAS: 698387-09-6) with high quality. Ruifu has been supplying APIs (active pharmaceutical ingredients) and pharmaceutical intermediates more than 15 years.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Neratinib or other products, please contact us by e-mail:

698387-09-6 - Chemical Properties:

Chemical Name Neratinib
Synonyms HKI-272; HKI272; HKI 272; (2E)-N-[4-[3-Chloro-4-(2-Pyridinylmethoxy)anilino]-3-Cyano-7-Ethoxy-6-Quinolinyl]-4-(Dimethylamino)-2-Butenamide
Stock Status In Stock, Commercial Production  
CAS Number 698387-09-6
Neratinib Maleate CAS  915942-22-2
Molecular Formula C30H29ClN6O3
Molecular Weight 557.05 g/mol
Melting Point 182.0 to 186.0℃ 
Density 1.33 
Sensitive Heat Sensitive 
Storage Temperature Store Long-Term at 2-8℃
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
API (Active Pharmaceutical Ingredient) 
Caution Not For Human or Veterinary Use. For Research Use Only.
Brand Ruifu Chemical

698387-09-6 - Specifications:

Items Specifications  Results
Appearance Faint Yellow to Yellow Solid Powder    Yellow Solid Powder    
Assay / Analysis Method ≥99.0% (HPLC)  99.1%
Infrared Spectrum Conforms to Structure   Conforms 
NMR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications

698387-09-6 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

698387-09-6 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

698387-09-6 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: or 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

698387-09-6 - Risk and Safety:

HS Code 2933 4900.40                             

698387-09-6 - Application:

Neratinib (HKI-272) (CAS: 698387-09-6) is developed by US Wyeth company is an irreversible epidermal growth fac tor receptor(EGFR) inhibitor. Neratinib is a multiple target point of small molecule tyrosine kinase inhibitors to HER 2 and HER1 after Lapatinib, and is an irreversible ErbB receptor tyrosine kinase inhibitor. Neratinib could selectively inhibit HER-1 and HER-2 of EGFR family(IC50 was 92 nmol/L and 59 nmol/L, respectively). Clinical research showed that Neratinib exerted significant therapeutic effect on non-small cell lung cancer, colon cancer, and breast cancer. The phaseII clinical trial indicated that Neratinib showed good efficacy and tolerance to HER-2 positive patients with advanced breast cancer who had been received or not Trastuzuma b treatment. 

  • Write your message here and send it to us