Ezetimibe Intermediate ZT-5 CAS 189028-95-3 Purity ≥98.0% (HPLC) Factory High Quality

Short Description:

Name: Ezetimibe Intermediate ZT-5

CAS: 189028-95-3

Appearance: White or Off-White Powder

Purity: ≥98.0% (HPLC)

ZT-4: ≤1.0% Enantiomer: ≤0.2%

Intermediate of Ezetimibe (CAS: 163222-33-1) in the treatment of Hypercholesterolemia

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Product Detail

Product Tags

Description:

Chemical Properties:

Chemical Name	(4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
Synonyms	Ezetimibe Intermediate ZT-5
CAS Number	189028-95-3
CAT Number	RF-PI146
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C20H20FNO4
Molecular Weight	357.38
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White or Off-White Powder
Purity / Analysis Method	≥98.0% (HPLC)
Impurity ZT-4	≤1.0%
Enantiomer	≤0.20%
Single Impurity	≤1.5%
Total Impurities	≤2.0%
Test Standard	Enterprise Standard
Usage	Ezetimibe (CAS: 163222-33-1) Intermediate

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Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one (CAS: 189028-95-3) with high quality. It is an intermediate of Ezetimibe (CAS: 163222-33-1)

Ezetimibe (CAS: 163222-33-1) is ananti-hyperlipidemic drug used for lowering the plasma cholesterol levels. It is indicated as an adjunctive therapy to diet for the reduction of high-level total-C, LDL-C, and ApoB in patients suffering primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors.Ezetimibe does not inhibit the cholesterol synthesis in the liver, or increase bile acid excretion.