Ezetimibe CAS 163222-33-1 Purity 98.5%~102.0% (HPLC) API High Purity

Short Description:

Name: Ezetimibe

CAS: 163222-33-1

Appearance: White to Off-White Powder

Purity: 98.5%~102.0% (HPLC)  

Ezetimibe (CAS: 163222-33-1) in the treatment of Hypercholesterolemia

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


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Description:

Manufacturer Supply; High Quality and Competitive Price
Commercial Supply Ezetimibe (CAS: 163222-33-1) Related Intermediates:
(S)-(+)-4-Phenyl-2-oxazolidinone CAS: 99395-88-7
(R)-(+)-2-Methyl-CBS-oxazaborolidine CAS: 112022-83-0
4-(4-Fluorobenzoyl)butyric acid CAS: 149437-76-3
4-[[(4-Fluorophenyl)imino]methyl]-phenol CAS: 3382-63-6
N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline CAS: 70627-52-0
(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one CAS 190595-65-4
(4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone CAS: 189028-93-1
(4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one CAS: 189028-95-3
Ezetimibe CAS: 163222-33-1

Chemical Properties:

Chemical Name (3R,4S)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one 
Synonyms Ezetimibe 
CAS Number 163222-33-1
CAT Number RF-API02
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C24H21F2NO3
Molecular Weight 409.43
Melting Point 162.0 ~ 166.0℃
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder
Identification By IR, HPLC
Purity / Analysis Method 98.5%~102.0% (HPLC)
Specific Rotation -25.0°~ -30.0°
Moisture (K.F) ≤0.50%
Sulfated Ash ≤0.10%
Heavy Metals ≤0.002%
Enantiomer ≤0.30%
Single Max. Impurity ≤0.50%
Total Impurities ≤1.0%
Test Standard Enterprise Standard
Usage Ezetimibe (CAS: 163222-33-1) API

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

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FAQ:

2

Application:

Ezetimibe (CAS: 163222-33-1) is a cholesterol transport inhibitor that binds to NPC1L1, belongs to a class of substances used to lower cholesterol levels in the blood is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin) when statins alone do not control cholesterol. Ezetimibe is orally administered alone or as a combination tablet with either simvastatin or atorvastatin. Ezetimibe was approved in 2002 by the FDA, under the trade name Zetia. It is approved for use in the EU as Ezetrol and other trade names. It is produced through a multi-step chemical process. 

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