Edoxaban Tosylate Monohydrate CAS 1229194-11-9 Purity >99.0% (HPLC)

Short Description:

Chemical Name: Edoxaban Tosylate Monohydrate 

CAS: 1229194-11-9

Purity: >99.0% (HPLC)

Appearance: White to Off-White Powder 

Anticoagulant, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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1229194-11-9 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Edoxaban Tosylate Monohydrate (CAS: 1229194-11-9) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase, Please contact: alvin@ruifuchem.com

1229194-11-9 - Chemical Properties:

Chemical Name Edoxaban Tosylate Monohydrate 
Synonyms Edoxaban p-Toluenesulfonate Monohydrate; Edoxaban Tosylate Hydrate; DU-176b Monohydrate; N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-[(Dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-Tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-Toluenesulfonate Monohydrate
Stock Status In Stock, Commercial Production  
CAS Number 1229194-11-9
Molecular Formula C31H38ClN7O7S2
Molecular Weight 720.26 g/mol
Melting Point >252℃(dec.) 
Sensitive Hygroscopic 
Solubility Soluble in Methanol, Slightly Soluble in Water 
COA & MSDS Available
Origin Shanghai, China
Category   API (Active Pharmaceutical Ingredient); Anticoagulant
Brand Ruifu Chemical

1229194-11-9 - Specifications:

Items Specifications  Results
Appearance White to Off-White Powder  Conforms   
Identification HPLC/NMR Conforms
Water by Karl Fischer  2.0%~3.5%  1.3%  
Specific Optical -89.0° to -99.0° -96.2°
Residue on Ignition <0.10% 0.04% 
Isomer <0.05% <0.05%  
Related Substances
Single Impurity  <0.10% 0.08% 
Total Impurities <0.50% 0.13%
Heavy Metals (Pb) <20ppm <20ppm 
Residual Solvents
Methanol  <0.10% 0.03%
Acetonitrile   <0.041% Undetected
Dichloromethane  <0.06% Undetected
Hexane <0.029% Undetected
Tetrahydrofuran  <0.072% Undetected
Toluene <0.089% Undetected
Purity / Analysis Method >99.0% (HPLC)  99.87% 
Infrared Spectrum Conforms to Structure Conforms   
NMR Spectrum Conforms to Structure Conforms   
Conclusion The product has been tested and complies with the given specifications

Note:

The listed products which involve patents, are only for research and development, and not used for sales.
Regulated products will be sold in strict accordance with the laws of China and the laws of the buyer's country.
All products are not for human use, and all risks associated with the sale to the country that constitutes a patent infringement shall be borne by the buyer.  

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

1229194-11-9 - Application:

Edoxaban Tosylate Monohydrate (CAS: 1229194-11-9), is a selective inhibitor of factor Xa and an anticoagulant with oral effect.
On January 8, 2015, the US FDA approved the anticoagulant drug Idusaban (Edoxaban) of Daiichi Sankyo Pharmaceutical Company of Japan, with the trade name Savaysa. Idusaban is a selective coagulation factor Xa inhibitor oral tablet for the prevention and treatment of deep vein thrombosis and pulmonary embolism. It is used to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF).  

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