Dimethylcarbamoyl Chloride CAS 79-44-7 Purity >98.0% (GC)

Dimethylcarbamoyl Chloride (CAS: 79-44-7) has been used primarily as a chemical intermediate in the production of dyes, pharmaceuticals, pesticides, agrochemicals, and other fine organic chemicals. However, due to its high toxicity that may induce both acute effects and be of cancer risk, it is strictly limited for application. Dimethylcarbamoyl Chloride is a highly reactive and corrosive compound that requires careful handling and proper safety precautions.
Dimethylcarbamoyl Chloride is an important reagent in organic synthesis. Dimethylcarbamoyl Chloride is an acylating agent that is used to convert amines into amides, and to introduce the carbamate functionality into various compounds, and to synthesize various heterocyclic compounds, such as pyrroles, pyrazoles, and oxazoles. Dimethylcarbamoyl Chloride derivatives have potential applications in drug development and therapy.
Dimethylcarbamoyl Chloride appears as a clear liquid at room temperature with a pungent odor and a tear-penetrating effect, which decomposes rapidly in water. Dimethylcarbamoyl Chloride is similar with an acid chloride whose chlorine atom can be exchanged for other nucleophiles. Therefore, it is capable of reacting with alcohols, phenols and oximes to the corresponding N, N-Dimethylcarbamates, with thiols to thiolourethanes, with amines and hydroxylamine to substituted ureas, and with imidazoles and triazoles to carbamoylazoles.