D-4-Hydroxyphenylglycine CAS 22818-40-2 Purity >99.0% (Titration) (HPLC)

Short Description:

Chemical Name: D-4-Hydroxyphenylglycine

Synonyms: H-D-Phg(4-OH)-OH 

CAS: 22818-40-2

Purity: >99.0% (Titration) (HPLC)

Appearance: White or Off-White Crystalline Powder

Production Capacity 4000 Tons per Year, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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22818-40-2 - Description:

Ruifu Chemical is the leading manufacturer of D-4-Hydroxyphenylglycine (H-D-Phg(4-OH)-OH; 4-Hydroxy-D-Phenylglycine) (CAS: 22818-40-2) with high quality, production capacity 4000 tons per year. Mainly used in the production of semisynthetic β-lactam antibiotics, such as Penicillin, Amoxicillin, and Cefadroxil, Cephalosporins. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase D-4-Hydroxyphenylglycine, Please contact: alvin@ruifuchem.com

22818-40-2 - Chemical Properties:

Chemical Name D-4-Hydroxyphenylglycine 
Synonyms H-D-Phg(4-OH)-OH; 4-Hydroxy-D-Phenylglycine; 4-Hydroxy-D-(-)-2-Phenylglycine; D-(-)-4-Hydroxyphenylglycine; D-p-Hydroxyphenylglycine; D-(-)-2-(4-Hydroxyphenyl)glycine; D-(-)-2-(p-Hydroxyphenyl)glycine; (R)-(-)-2-Amino-2-(4-Hydroxyphenyl)acetic Acid; D-(-)-α-(4-Hydroxyphenyl)glycine; D-(-)-α-Amino-4-Hydroxyphenylacetic Acid; D-α-p-Hydroxyphenylglycine
Impurity Cefadroxil EP Impurity A; Amoxicillin EP Impurity A 
Stock Status In Stock, Production Capacity 4000 Tons per Year
CAS Number 22818-40-2 
Molecular Formula C8H9NO3
Molecular Weight 167.16 g/mol
Melting Point 238.0~241.0℃(dec.)(lit.) 
Density 1.396 g/cm3 at 20℃
Solubility in 1mol/L HCl  Almost Transparency 
COA & MSDS Available
Origin of Product    China
Product Categories
Pharmaceutical Intermediates; Unnatural Amino Acid Derivatives
Brand Ruifu Chemical

22818-40-2 - Specifications:

Items Specifications  Results
Appearance White or Off-White Crystalline Powder Complies             
Specific Rotation [a]20/D -155.0° ~ -161.0° (C=1 in 1M HCl) -156.1°
Water by Karl Fischer  <0.50% 0.12%
Assay / Analysis Method
>99.0% (Titration)  99.3%
Purity / Analysis Method >99.0% (HPLC)  >99.0% 
Infrared Spectrum Consistent with Structure Complies
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

22818-40-2 - Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg paper bag with double-layer PE inner bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Incompatible with oxidizing agents.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery. 

22818-40-2 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

22818-40-2 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

22818-40-2 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 3
TSCA Yes
HS Code 2922501000

22818-40-2 - Application:

D-4-Hydroxyphenylglycine (H-D-Phg(4-OH)-OH; 4-Hydroxy-D-Phenylglycine) (CAS: 22818-40-2) is used as pharmaceutical intermediates, is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Penicillin (CAS: 69-57-8), Amoxicillin (CAS: 26787-78-0) and Cefadroxil (CAS: 66592-87-8), Cephalosporins and other pharmaceutical synthesis.

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