Carboxymethyl-β-Cyclodextrin CAS 218269-34-2 (CM-β-CD)

Short Description:

Chemical Name: Carboxymethyl-β-Cyclodextrin

Synonyms: CM-β-CD; CMBCD 

CAS: 218269-34-2

Assay: >98.0%  

White Powder, Sweet, Insipid and Innocuous

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Pharma Grade Cyclodextrins:

218269-34-2 - Description:

Ruifu Chemical is the leading manufacturer of Carboxymethyl-β-Cyclodextrin (CM-β-CD; CMBCD) (CAS: 218269-34-2) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Carboxymethyl-β-Cyclodextrin, Please contact: alvin@ruifuchem.com

218269-34-2 - Chemical Properties:

Chemical Name Carboxymethyl-β-Cyclodextrin 
Synonyms CM-β-CD; CMBCD; Carboxymethyl-beta-Cyclodextrin; Carboxymethyl-Beta-Cyclodextrin Sodium Salt
Stock Status In Stock, Production Capacity 100 MT per year
CAS Number 218269-34-2 (Free Base)
Molecular Formula C56H84O49.xNa
Molecular Weight 1541.24+x(22.99) g/mol
Melting Point ~245℃(dec.)   
Density 1.82±0.10 g/cm3 
Sensitive Hygroscopic
COA & MSDS Available
Shelf Life 24 Months if Stored Properly 
Origin Shanghai, China
Brand Ruifu Chemical

218269-34-2 - Specifications:

Items Specifications Results
Appearance White Powder, Sweet, Insipid and Innocuous   Conforms                       
Assay ≥98.0% 99.3%
Degree of Substitution 7.0
pH 5.0~7.5 6.57
Loss on Drying ≤4.0% 3.2% 
Residue on Ignition ≤20.0% 18.6%   
Heavy Metals ≤0.0025% <0.0025%
Arsenic Salt ≤0.0002% <0.0002%
Microbiological Test
Total Aerobic Microbial Counts  ≤1000cfu/g 180cfu/g  
Total Molds & Yeasts Counts
≤100cfu/g N/D
Pathogenic Bacteria Not Detectable  None
Infrared Spectrum Conforms to Structure Conforms                       
Conclusion The product has been tested and complies with the given specifications 
Application Pharmaceuticals, Food, Cosmetics etc. 

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 10kg/20kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Store away from oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

218269-34-2 - Safety Information:

WGK Germany 3
FLUKA BRAND F CODES 3                                              

218269-34-2 - Application:

Carboxymethyl-β-Cyclodextrin (CM-β-CD; CMBCD) (CAS: 218269-34-2)
* In Pharmaceutical field:
1.Carbxymetohyl-Beta-Cyclodextrin can increase the solubility of the medicine and biological availability
2.Carbxymetohyl-Beta-Cyclodextrin can also add up the good effect and decrease the dose.
3.Carbxymetohyl-Beta-Cyclodextrin can control or adjust the reactive speed, lower the drug toxicity and enhance the stability of drugs
4.Carbxymetohyl-Beta-Cyclodextrin is more effective for the oil-soluble molecules of water-soluble.
* In food and spice field:
Carbxymetohyl-Beta-Cyclodextrin can improve the stability and long effect of nutritional elements also it can cover up and correct the ordor and taste of food nutrition elements.
* In cosmetics field:
Carbxymetohyl-Beta-Cyclodextrin can reduce the stimulation to the skin , strengthen the stability of the matter, and avoid volatility and oxidation of the nutrition elements.

218269-34-2 - Reference:

Carboxymethyl-β-Cyclodextrin (CM-β-CD; CMBCD) (CAS: 218269-34-2), In solution that pH<4, Carboxymethyl-β-Cyclodextrin (CM-β-CD) solubility is low. But in pH>4 solution that carboxyl group dissociate, CM-β-CD can dissolved in water in any concentration. It has a good solubility in the human intestinal environment that pH is 6-7. CM-β-CD that has lower hemolysis than HP-β-CD (CAS: 128446-35-5) can be used in prolonged release formulations. 

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