(-)-Corey Lactone 4-Phenylbenzoate Alcohol BPCOD CAS 31752-99-5 Purity >99.0% (HPLC) Prostaglandin Intermediate Factory

Short Description:

Name: (-)-Corey Lactone 4-Phenylbenzoate Alcohol 

Synonyms: BPCOD

CAS: 31752-99-5

Purity: >99.0% (HPLC) 

White to Yellowish Powder or Crystalline Powder

Intermediate of Prostaglandin, Latanoprost

Contact: Dr. Alvin Huang  

Mobile/Wechat/WhatsApp: +86-15026746401 

E-Mail: alvin@ruifuchem.com


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Description:

Chemical Properties:

Chemical Name (-)-Corey Lactone 4-Phenylbenzoate Alcohol
Synonyms (-)-Corey Lactone 4-Phenylbenzoate; (-)-Corey lactone 4-PBP; BPCOD; (3aα,4α,5β,6aα)-(-)-Hexahydro-4-(Hydroxymethyl)-2-oxo-2H-Cyclopenta[b]furan-5-yl 1,1′-Biphenyl-4-Carboxylate; (3aR,4S,5R,6aS)-Hexahydro-4-Hydroxymethyl-5-(4-Phenylbenzoyloxy)cyclopenta[b]furan-2-one
CAS Number 31752-99-5
CAT Number RF-PI1998
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C21H20O5
Molecular Weight 352.38
Density 1.30±0.10 g/cm3
Water Solubility H2O: Insoluble
Solubility Soluble in Chloroform and Methanol
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Yellowish Powder or Crystalline Powder
Identification by HPLC The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard as obtained in the isomer
Melting Point 128.0~134.0℃
Purity / Analysis Method >99.0% (HPLC)
Water Content (K.F) <0.50%
Residue on Ignition <0.20%
Specific Rotation [α]20/D -85.0° to -89.0° (C=1.0, CHCl3)
(+) Isomer <0.10%
Maximum Single Impurity <0.50%
Total Impurities <1.00%
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Prostaglandin Intermediates; Latanoprost Intermediate

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

(-)-Corey Lactone 4-Phenylbenzoate Alcohol (CAS: 31752-99-5) is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α. Used in Prostaglandin Derivatives; Used as Prostaglandin Series Intermediates. Prostaglandins are a kind of important endogenous physiological active substances and important mediators of various physiological processes, with high pharmacological activity. Clinically, Prostaglandins are all synthesized artificially. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α. (-)-Corey Lactone 4-Phenylbenzoate Alcohol is an intermediate of Latanoprost (CAS: 130209-82-4). Latanoprost is a prostaglandin F2a analogue. It is a prostanoid selective FP receptor agonist that is believed to reduce the intraocular pressure (IOP) by increasing the outflow of aqueous humor. It is used to treat certain kinds of glaucoma(open-angle glaucoma ocular hypertension). It is also used to treat a condition called hypertension of the eye. Latanoprost is used to increase the natural outflow of fluid (aqueous humor) from inside the eye into the bloodstream. It appears to work by increasing the outflow of fluid from the eye. This lowers the pressure in the eye. 

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