Prostaglandin E1 (Alprostadil; PGE1) CAS 745-65-3 Assay 95.0~102.5%

Short Description:

Chemical Name: Prostaglandin E1

Synonyms: Alprostadil; PGE1 

CAS: 745-65-3

Assay: 95.0~102.5% (Anhydrous and Solvent Free Basis) 

White or Slightly Yellowish Crystalline Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401


Product Detail

Related Products

Product Tags

745-65-3 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Prostaglandin E1 (Alprostadil; PGE1) (CAS: 745-65-3) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Prostaglandin E1, Please contact:

745-65-3 - Chemical Properties:

Chemical Name Prostaglandin E1   
Synonyms Alprostadil; PGE1; (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid; (11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-13-en-1-oic Acid; ent-PGE1
Stock Status In Stock, Commercial Production  
CAS Number 745-65-3
Molecular Formula C20H34O5
Molecular Weight 354.49 
Melting Point 115.0 to 119.0℃ 
Density 1.13 
Sensitive Heat Sensitive 
Water Solubility  Insoluble in Water 
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical


Items Specifications Results
Appearance White or Slightly Yellowish Crystalline Powder Conforms
Identification (1) HPLC The retention time of the major peak in the chromatogram of Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay Conforms
Identification (2) IR Absorbance Spectrum Both the test sample and the reference standard exhibit the same intensity of absorption at the same wave number(wavelengths). (potassium bromide disk method) Conforms
Optical Rotation -60.0° to -70.0° (Anhydrous Substance) -69.4°
Water by Karl Fischer <0.50% 0.19%
Residue on Ignition <0.50% 0.21%
Related Substances 
Impurity A <1.50% Not Detected
Impurity B <0.50% Not Detected
Any Other Impurity <0.90% 0.26%
N.M.T One Impurity <0.50% Not Detected
Total Impurities <1.50% 0.51%
Residual Solvents
Ethyl Acetate <0.50% 0.0484%
n-Heptane <0.50% 0.0056%
Acetone <0.50% Not Detected
n-Hexan <0.029% Not Detected
Assay 95.0~102.5% (Anhydrous and Solvent Free Basis)  99.8%
Conclusion Conforms to the Requirements of EP7.0 


Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (-20℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 


Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system


How to Purchase? Please contact Dr. Alvin Huang: or 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

745-65-3 - Risk and Safety:

Risk Codes R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R61 - May cause harm to the unborn child
Safety Description S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs UN 2811 6.1/PG 3
WGK Germany 3
RTECS GY4569800
HS Code 2937500090
Hazard Class 6.1(b)
Packing Group III

745-65-3 - Application:

Prostaglandin E1 (Alprostadil; PGE1) (CAS: 745-65-3) is a biologically active substance widely present in the body. It is a member of the prostaglandin family and is recognized as an endogenous physiologically active substance. Prostaglandin E1 acts directly on vascular smooth muscle, dilates blood vessels, increases blood flow, improves microcirculation perfusion, inhibits platelet aggregation and thromboxane A2 production, and inhibits atherosclerosis, lipid plaque and immune complex formation; dilate peripheral small vessels and coronary arteries, reduce peripheral vascular resistance and blood pressure, protect platelet membrane, prevent thrombosis; Protect ischemic myocardium, reduce myocardial infarction area; Anti-heart failure; Dilate renal vessels, increases renal blood flow, removes non-protein nitrogen, regulates water-sodium balance, has a diuretic and protective effect on renal function.
Used for diabetic neuropathy, myocardial infarction, thrombotic vasculitis, arteriosclerosis obliterans, central retinal vein thrombosis. It is used in the treatment of hepatitis cirrhosis, cerebral infarction, diabetes, impotence, respiratory diseases. Liver damage is not serious childA, class B patients, especially patients with antithrombin level childA China effect. For induction of labor, oxytocin, renal insufficiency, treatment mumps, pancreatitis. Injection of Prostaglandin E1 is mainly applied to myocardial infarction, heart failure, thrombotic vasculitis, chronic arterial occlusive disease, central retinal vein thrombosis, platelet protection for extracorporeal circulation, arteriography, revascularization surgery.  

  • Write your message here and send it to us