(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine CAS 608141-42-0 Purity ≥99.0% (HPLC) Chiral Purity ≥99.0% Apremilast Intermediate Factory

Short Description:

Chemical Name: (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine

CAS: 608141-42-0

Purity: ≥99.0% (HPLC)

Chiral Purity: ≥99.0%

Appearance: White to Off-White Solid

Intermediate of Apremilast (CAS: 608141-41-9) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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608141-42-0 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine (CAS: 608141-42-0) with high quality, intermediate of Apremilast (CAS: 608141-41-9). Apremilast is used for the treatment of active psoriatic arthritis (PsA) and moderate to severe chronic plaque psoriasis (PSOR). Ruifu Chemical can provide high-quality Apremilast intermediates and impurities.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Apremilast intermediates and impurities or other products, please e-mail: alvin@ruifuchem.com

Intermediates of Apremilast:

608141-42-0 - Chemical Properties:

Chemical Name (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine 
Synonyms Apremilast Intermediate II; APST-2; (alphaS)-3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)methyl]-Benzenemethanamine; (αS)-3-Ethoxy-4-Methoxy-α-[(Methylsulfonyl)methyl]benzenemethanamine; 3-Ethoxy-4-Methoxy-α-[(Methylsulfonyl)methyl]-(αS)-Benzenemethanamine; (1S)-1-(3-Ethoxy-4-Methoxy-phenyl)-2-Methanesulfonyl-Ethylamine; (1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine; (1S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-Methanesulfonylethan-1-Amine
Stock Status In Stock, Commercial Production  
CAS Number 608141-42-0
Molecular Formula C12H19NO4S
Molecular Weight 273.35 g/mol
Melting Point 106.0~108.0℃ 
Density 1.195±0.06 g/cm3 
Storage Temperature Store Long-Term at 2-8℃
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Apremilast Intermediate 
Brand Ruifu Chemical

608141-42-0 - Specifications:

Items Specifications  Results
Appearance White or Off-White Solid  White Solid  
Identification RT (by HPLC) Conforms with Reference Standard Conforms 
Melting Point 106.0~108.0℃ 106.0~108.0℃
Water by Karl Fischer  ≤0.50% 0.22%
Residue on Ignition ≤0.20% 0.02%
Any Single Unknown Impurity ≤0.10% 0.08%
Purity / Analysis Method ≥99.0% (HPLC)    99.85%
Chiral Purity (e.e.%)   ≥99.0% 99.99%
Enantiomer ≤0.10% 0.01%
1H NMR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Apremilast (CAS: 608141-41-9) 

608141-42-0 - Package/Storage/Shipping:

Package: Fluorinated bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

608141-42-0 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

608141-42-0 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

608141-42-0 - Safety Information:

HS Code 2934999099                                  

608141-42-0 - Application:

(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine (CAS: 608141-42-0), intermediate of Apremilast (CAS: 608141-41-9). Apremilast (Otezla) was approved by the FDA on March 21, 2014 for the treatment of adult patients with active psoriatic arthritis. Apremilast is also used to treat moderate to severe plaque psoriasis in certain patients.

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