Apremilast CAS 608141-41-9 Purity >99.0% (HPLC) PDE-4 Inhibitor

Short Description:

Chemical Name: Apremilast

Synonyms: Otezla; CC-10004

CAS: 608141-41-9

Purity: >99.0% (HPLC)

Appearance: White to Pale Yellow Solid

A Potent PDE4 (Phosphodiesterase 4) Inhibitor

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

608141-41-9 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Apremilast (CC-10004) (CAS: 608141-41-9) with high quality, a potent PDE4 (phosphodiesterase 4) inhibitor. Apremilast is used for the treatment of active psoriatic arthritis (PsA) and moderate to severe chronic plaque psoriasis (PSOR).
Ruifu Chemical can provide high-quality Apremilast intermediates and impurities.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Apremilast intermediates and impurities or other products, please e-mail: alvin@ruifuchem.com

Intermediates of Apremilast:

Apremilast	CAS 608141-41-9
3-Acetamidophthalic Anhydride	CAS 6296-53-3
3-Ethoxy-4-Methoxybenzonitrile	CAS 60758-86-3
3-Ethoxy-4-Methoxybenzaldehyde	CAS 1131-52-8
1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine	CAS 253168-94-4
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine	CAS 608141-42-0
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylamine N-Acetyl-L-LeucineSalt	CAS 608141-43-1

608141-41-9 - Chemical Properties:

Chemical Name	Apremilast
Synonyms	Otezla; CC-10004; CC10004; Apster; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; (S)-4-Acetylamino-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]isoindoline-1,3-dione; N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide; N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl}acetamide; (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
Stock Status	In Stock
CAS Number	608141-41-9
Molecular Formula	C22H24N2O7S
Molecular Weight	460.5 g/mol
Melting Point	152.0~156.0℃
Density	1.381 g/cm3
Solubility	DMSO (>80 mg/ml)
Storage Temperature	Store Long-Term at -20℃
Shipping Conditions	Shipped Under Ambient Temperature for Short Term
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	API (Active Pharmaceutical Ingredient)
Caution	For Research Use Only! Not For Use in Humans!
Brand	Ruifu Chemical

608141-41-9 - Specifications:

Items	Specifications	Results
Appearance	White to Pale Yellow Solid	Off-White Solid
Purity / Analysis Method	>99.0% (HPLC)	99.5%
Infrared Spectrum	Conforms to Structure	Conforms
NMR Spectrum	Conforms to Structure	Conforms
Conclusion	The product has been tested and complies with the given specifications

608141-41-9 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store long-term at -20℃. Keep away from incompatible substances. Protect from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

608141-41-9 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

608141-41-9 - Application:

Apremilast (CC-10004; Otezla) (CAS: 608141-41-9) is the first and only oral phosphodiesterase IV (PDE- 4) inhibitor and anti-tumor necrosis factor alpha (TNFa) agent launched in the USA by Celgene for the treatment of active psoriatic arthritis (PsA). Apremilast was also approved for the treatment of moderate to severe plaque psoriasis in the USA. Later, this drug was also approved in the European Union (EU) for both indications.

608141-41-9 - Patent Statement:

The listed products which involve patents, are only for research and development ,and not used for sales.
Regulated products will be sold in strict accordance with the laws of China and the laws of the buyer's country.
All products are not for human use ,and all risks associated with the sale to the country that constitutes a patent infringement shall be borne by the buyer.