Carbimazole CAS 22232-54-8 Assay >98.5% Factory

Short Description:

Chemical Name: Carbimazole 

CAS: 22232-54-8

Assay: >98.5%

Appearance: White or Pale Yellow Crystalline Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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22232-54-8 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Carbimazole (CAS: 22232-54-8) with high quality. Ruifu Chemical offers advanced, high quality pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Carbimazole (CAS: 22232-54-8), Please contact: alvin@ruifuchem.com

22232-54-8 - Chemical Properties:

Chemical Name Carbimazole 
Synonyms Ethyl 3-Methyl-2-Thionoimidazoline-1-Carboxylate; 1-Ethoxycarbonyl-3-Methyl-2-Thioxo-4-Imidazoline; 3-Methyl-2-Thionoimidazoline-1-Carboxylic Acid Ethyl Ester; 1-Methyl-2-Imidazolethiol Ethyl Carbamate; Ethyl 3-Methyl-2-Thioxo-4-Imidazoline-1-Carboxylate; 2,3-Dihydro-3-Methyl-2-thioxo-1H-Imidazole-1-Carboxylic Acid Ethyl Ester; Athyromazole; Neomercazole
Stock Status In Stock, Commercial Production  
CAS Number 22232-54-8
Molecular Formula C7H10N2O2S
Molecular Weight 186.23 g/mol
Melting Point 122.0 to 125.0℃ 
Density 1.319 
Store Under Inert Gas Store Under Inert Gas
Sensitive Air Sensitive, Light Sensitive 
Solubility Slightly Soluble in Water, Soluble in Acetone and in Alcohol
COA & MSDS Available
Place of Origin  Shanghai, China
Product Categories
API (Active Pharmaceutical Ingredient)  
Caution Not Intended for Human Use. For Research Use Only
Brand Ruifu Chemical

22232-54-8 - Specifications:

Items Specifications  Results
Appearance White or Pale Yellow Crystalline Powder   Complies 
Solubility Slightly Soluble in Water, Soluble in Acetone and Alcohol Complies 
Melting Point 122.0~125.0℃ 122.2~123.8℃    
Loss on Drying <0.50% 0.18%
Residue on Ignition <0.10% 0.05%
Heavy Metals (Pb) <10ppm 5ppm 
Related Substances
Methimazole <0.50% 0.18%
Any Other Impurity <0.10% <0.10%
Assay / Analysis Method >98.5% (HPLC)  99.8% 
Infrared Spectrum Consistent with Structure Complies
NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

22232-54-8 - Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Air sensitive, light sensitive. Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

22232-54-8 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

22232-54-8 - Risk and Safety:

Risk Codes R22 - Harmful if swallowed
R36 - Irritating to the eyes
R43 - May cause sensitization by skin contact
Safety Description S22 - Do not breathe dust.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs 3335
WGK Germany 3
RTECS NJ2441000
HS Code 2933290090

22232-54-8 - Application:

Carbimazole (CAS: 22232-54-8) is used as thyroid inhibitor. A suppressor of thyroid hormone production.
Carbimazole, a prodrug of Methimazole (CAS: 60-56-0), is used in the treatment of hyperthyroidism. Carbimazole is a thionamide antithyroid drug.
Carbimazole is a drug primarily used in the treatment of hyperthyroidism, a condition caused by an overproduction of the thyroid hormone. Carbimazole is an antithyroid medication that works by blocking the production of thyroid hormones and is used to reduce the symptoms of hyperthyroidism. Carbimazole is a prodrug, meaning that it is converted to its active form, methimazole, in the body. Carbimazole is available in tablet form and is usually taken orally, either once or twice a day.
Carbimazole is a precursor to Methimazole, with a similar structure but multi-sided chain, which is quickly removed after entering the body and is completely converted to Methimazole. Therefore, its pharmacological action, in vivo process, indications, adverse reactions and precautions are similar to those of Methimazole. Carbimazole is commonly used in the United Kingdom, Hong Kong and other places for anti-thyroid treatment.
Because Carbimazole has to be gradually hydrolyzed in the body and converted into Methimazole, it works, so Carbimazole may not be as effective as propyrimidine and Methimazole in the short term at the beginning of application, but it is not appropriate to use too large doses to prevent adverse reactions. 

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