Bz-rA Phosphoramidite CAS 104992-55-4 Purity ≥98.0% (HPLC) Purity ≥98.0% (31P-NMR) RNA Phosphoramidites

Short Description:

Chemical Name: Bz-rA Phosphoramidite

Synonyms: DMT-2′O-TBDMS-rA(bz) Phosphoramidite

CAS: 104992-55-4

Purity: ≥98.0% (HPLC) 

Purity: ≥98.0% (31P-NMR) 

Appearance: White or Off-White Powder 

RNA Phosphoramidites; Modified Nucleotides

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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RNA Phosphoramidites:

104992-55-4 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Bz-rA Phosphoramidite (DMT-2′O-TBDMS-rA(bz) Phosphoramidite) (CAS: 104992-55-4) with high purity and low impurities, is used in the synthesis of DNA and RNA oligonucleotides. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Bz-rA Phosphoramidite or other products, please contact us by e-mail: alvin@ruifuchem.com

104992-55-4 - Chemical Properties:

Chemical Name Bz-rA Phosphoramidite 
Synonyms DMT-2′O-TBDMS-rA(bz) Phosphoramidite; 2'-TBDMS -Bz-rA-CE-Phosphoramidite; 5'-DMT-2'-O-TBDMS- N6-Benzoyl-Adenosine Phosphoramidite; N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine; 3′-[2-Cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Stock Status In Stock 
CAS Number 104992-55-4
Molecular Formula C53H66N7O8PSi
Molecular Weight 988.19 g/mol
Storage Conditions Inert Atmosphere, Store in Freezer, Under -20℃, Under Nitrogen 
Shipping Conditions Shipped Under Ambient Temperature For Short Term 
COA & MSDS Available
Product Categories RNA Phosphoramidites; Modified Nucleotides
Origin of Product    Shanghai, China
Brand Ruifu Chemical

104992-55-4 - Specifications:

Items Specifications  Results
Appearance White or Off-White Powder    White Powder    
Solution Clarity Test Clear Clear
UV Spectrum 200~350 nm, the maximum and minimum absorption
wavelengths differ from the standard spectrum by +2nm
Conforms 
Water Content   ≤0.30% (Karl Fischer)  Conforms   
Residual Solvent Content ≤3.00% (GC) Conforms   
Single Impurity ≤0.50% (HPLC)  Conforms   
Purity / Analysis Method ≥98.0% (HPLC)  98.5%
Purity / Analysis Method ≥98.0% (31P-NMR) Conforms   
1H NMR Spectrum Conforms to Structure   Conforms   
LC-MS Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications

104992-55-4 - Package/Storage/Shipping:

Package: 1g/10g/50g/100g/1kg/10kg/bulk. Amber glass screw cap vial or white plastic bottle.
Storage Condition: Keep the container tightly closed. Inert atmosphere, store in freezer, under -20℃, under nitrogen. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

104992-55-4 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

104992-55-4 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

104992-55-4 - Risk and Safety:

WGK Germany 3
HS Code 2934 9990.01                                               

104992-55-4 - Introduction:

Bz-rA Phosphoramidite (DMT-2′O-TBDMS-rA(bz) Phosphoramidite) (CAS: 104992-55-4) is used for ribonucleotides modification, it is a synthetic organic compound used in the synthesis of oligonucleotides. It is used as a building block in the synthesis of DNA and RNA oligonucleotides. Bz-rA Phosphoramidite is a versatile compound that can be used to synthesize a wide variety of nucleic acid sequences. It is also used in the synthesis of peptide nucleic acids (PNAs) and other related compounds.
Bz-rA Phosphoramidite is a 2'-O-Protected ribonucleoside phosphoramidite used as a key raw material for the automated solid-supported synthesis of oligonucleotide-based drugs. It is also used to synthesize 2'-O-guanidinopropyl-modified nucleoside phosphoramidites to incorporate into siRNAs targeting hepatitis B virus.

104992-55-4 - Scientific Research Applications:

Bz-rA Phosphoramidite (DMT-2′O-TBDMS-rA(bz) Phosphoramidite) (CAS: 104992-55-4) has a wide range of applications in the field of scientific research. Bz-rA Phosphoramidite is used in the synthesis of DNA and RNA oligonucleotides for applications such as gene expression studies, gene therapy, and DNA sequencing. Bz-rA Phosphoramidite is also used in the synthesis of peptide nucleic acids (Bz-rA Phosphoramidite) and other related compounds for applications such as drug delivery and gene delivery.
Bz-rA Phosphoramidite is also used in the synthesis of modified nucleic acids for applications such as DNA-protein interaction studies and DNA-protein binding assays.
Bz-rA Phosphoramidite is widely used in the field of molecular biology and genetics as a building block in the synthesis of oligonucleotides. It has several applications in scientific experiments, including DNA sequencing, site-directed mutagenesis, and gene expression analysis. Its incorporation into DNA can also be used to study the structure and function of DNA and its interactions with proteins.
Bz-rA Phosphoramidite is designed to form a stable linkage between the nucleotide and the growing oligonucleotide chain during the process of solid-phase synthesis. 

104992-55-4 - Future Directions:

There are a number of potential future directions for the use of Bz-rA Phosphoramidite. These include the development of new techniques for the synthesis of DNA and RNA oligonucleotides, the development of new methods for gene delivery and DNA-protein binding assays, and the development of new methods for the synthesis of modified nucleic acids. In addition, there is potential for the use of Bz-rA Phosphoramidite in the development of new drugs and drug delivery systems. Finally, there is potential for the use of Bz-rA Phosphoramidite in the development of new diagnostic and therapeutic tools.  

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