5-Formyl-2-Furanboronic Acid CAS 27329-70-0 Purity >98.0% (HPLC)

Short Description:

Chemical Name: 5-Formyl-2-Furanboronic Acid 

CAS: 27329-70-0

Purity: >98.0% (HPLC)

Appearance: Off-White to Light Yellow Powder 

Intermediate of Lapatinib / Lapatinib Ditosylate Monohydrate

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 5-Formyl-2-Furanboronic Acid (CAS: 27329-70-0) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 5-Formyl-2-Furanboronic Acid, Please contact: alvin@ruifuchem.com

Lapatinib Intermediates:

Chemical Properties:

Chemical Name 5-Formyl-2-Furanboronic Acid 
Synonyms 5-Formylfuran-2-Boronic Acid; 5-Formyl-2-Furanylboronic Acid; 2-Formylfuran-5-Boronic Acid; (5-Formylfuran-2-yl)boronic Acid; (5-Formyl-2-Furyl)boronic Acid; FFBA
Stock Status In Stock, Commercial Production  
CAS Number 27329-70-0
Molecular Formula C5H5BO4
Molecular Weight 139.90 g/mol
Melting Point 136℃(dec.) (lit.)   
Density 1.36±0.10 g/cm3 
Sensitive Air Sensitive 
Water Solubility  Insoluble in Water 
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance Off-White to Light Yellow Powder
Light Yellow Powder  
Water by Karl Fischer      <0.50% 0.11% 
Purity / Analysis Method >98.0% (HPLC)  99.79% 
Infrared Spectrum Consistent with Structure Complies 
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Air sensitive. Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Store away from air, moisture and oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory AuditFactory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
TransportationBy Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom SynthesisCan provide custom synthesis services to best fit your research needs.
Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

27329-70-0 - Safety Information:

Risk Codes
R34 - Causes burns
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39 - Wear suitable gloves and eye/face protection
S27 - Take off immediately all contaminated clothing.
UN IDs UN 3261 8/PG 3
WGK Germany 3
TSCA No
HS Code 2932190090
Hazard Note Irritant
Hazard Class IRRITANT, KEEP COLD
Packing Group Ⅲ

27329-70-0 - Application:

5-Formyl-2-Furanboronic Acid (CAS: 27329-70-0) is a boric acid intermediate, widely used in medicine and other fields. Boric acid compounds can react with chlorine, bromine or iodide aromatics and olefins in Suzuki, thereby connecting a variety of groups, and downstream products are very rich. 

5-Formyl-2-Furanboronic Acid is an intermediate of Lapatinib (CAS: 231277-92-2) / Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8). Lapatinib (lapatinib), trade name Tykerb, is an oral reversible small molecule tyrosine kinase inhibitor for HER-1/ HER-2. Lapatinib has a different mechanism of action from the approved humanized monoclonal antibody drug Herceptin, which can down-regulate cell proliferation signals by double blocking the HER-1/ HER-2 pathway. Lapatinib in combination with Capecitabine is suitable for the treatment of advanced or metastatic breast cancer patients with HER2(ErbB-2 overexpression) and previous treatment including anthracyclines, paclitaxel and trastuzumab.

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