Ethyl 2-Aminothiazole-5-Carboxylate CAS 32955-21-8 Purity >98.0% (HPLC) Dasatinib Intermediate

Short Description:

Chemical Name: Ethyl 2-Aminothiazole-5-Carboxylate 

CAS: 32955-21-8

Purity: >98.0% (HPLC)

Appearance: Light Brown to Off-White Powder or Crystals

Intermediate of Dasatinib / Dasatinib Monohydrate 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401


Product Detail

Related Products

Product Tags

32955-21-8 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Ethyl 2-Aminothiazole-5-Carboxylate (CAS: 32955-21-8) with high quality, intermediate of Dasatinib (CAS: 302962-49-8) and Dasatinib Monohydrate (CAS: 863127-77-9). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Dasatinib intermediates, Please contact:

Intermediates of Dasatinib:

32955-21-8 - Chemical Properties:

Chemical Name Ethyl 2-Aminothiazole-5-Carboxylate 
Synonyms 2-Aminothiazole-5-Carboxylic Acid Ethyl Ester; 2-Amino-5-Thiazole carboxylic Acid Ethyl Ester; 2-Amino-5-(Ethoxycarbonyl)thiazole; Ethyl 2-Amino-1,3-Thiazole-5-Carboxylate; Ethyl 2-Amino-5-Thiazolecarboxylate
Stock Status In Stock, Production Capacity 15 Tons per Year
CAS Number 32955-21-8
Molecular Formula C6H8N2O2S
Molecular Weight 172.20 g/mol
Melting Point 159.0 to 163.0℃ 
Density 1.336±0.06 g/cm3 
Store Under Inert Gas Store Under Inert Gas
Sensitive Light Sensitive, Moisture Sensitive, Heat Sensitive 
Solubility  Insoluble in Water. Slightly Soluble in Methanol
Storage Condition 2~8℃
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical

32955-21-8 - Specifications:

Items Specifications  Results
Appearance Light Brown to Off-White Powder or Crystals   Complies                
Melting Point 159.0~163.0℃ 161.2℃
Water by Karl Fischer  <0.50% 0.09%
Residue on Ignition <0.20% 0.05%
Purity / Analysis Method >98.0% (HPLC Area)  99.58%
Infrared Spectrum Consistent with Structure Complies
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application: Intermediate of Dasatinib (CAS: 302962-49-8) and Dasatinib Monohydrate (CAS: 863127-77-9).

32955-21-8 - Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

32955-21-8 - Method of Analysis:

Method of Analysis (CAS: 32955-21-8)
(HPLC) Method for Chemical Purity
Instrument Model: Agilent Technologies 1120 Compact LC
Column: YMC-Pack ODS-A(150*6.0)mml.D.S-5um12nm
Wavelength: 300nm
Mobile Phase: MeOH:(water+0.5%TEA)=65:35
Sample Concentration: 200μg/ml
Injection Volume: 20μL
Flow Rate: 1ml/min
Solvent: MeOH:Water=60:40 (V/V)
Column Temperature: At ambient temperature

32955-21-8 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

32955-21-8 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: or 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

32955-21-8 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany 2
HS Code 2934109099
Hazard Class IRRITANT

32955-21-8 - Application:

Ethyl 2-Aminothiazole-5-Carboxylate (CAS: 32955-21-8) with high quality, intermediate of Dasatinib (CAS: 302962-49-8) and Dasatinib Monohydrate (CAS: 863127-77-9).
May 2009, the US Food and Drug Administration (FDA) formally approved the sale of Dasatinib. Dasatinib has been clinically used for the treatment of various chronic myeloid leukemia (CML), including treatment of chronic myeloid leukemia which is resistant
Dasatinib is an oral Bcr-Abl tyrosine kinase inhibitor (inhibits the "Philadelphia chromosome") and Src family tyrosine kinase inhibitor approved for first line use in patients with chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It is being evaluated for use in numerous other cancers, including advanced prostate cancer.
Dasatinib is a cancer medicine that slows the growth and spread of cancer cells in the body. Dasatinib is suitable for chronic myeloid leukemia that is resistant or intolerant to treatment regimens including Imatinib Mesylate. 

  • Write your message here and send it to us