Dasatinib Intermediate CAS 302964-08-5 Purity >98.0% (HPLC)

Short Description:

Chemical Name: N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)amino]-5-Thiazolecarboxamide 

CAS: 302964-08-5

Purity: >98.0% (HPLC)

Appearance: Off-White to Light Yellow Solid

Intermediate of Dasatinib / Dasatinib Monohydrate 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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302964-08-5 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)amino]-5-Thiazolecarboxamide (CAS: 302964-08-5) with high quality, intermediate of Dasatinib (CAS: 302962-49-8) and Dasatinib Monohydrate (CAS: 863127-77-9). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Dasatinib intermediates, Please contact: alvin@ruifuchem.com

Intermediates of Dasatinib:

302964-08-5 - Chemical Properties:

Chemical Name N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)amino]-5-Thiazolecarboxamide
Synonyms Dasatinib Int N-1; Dasatinib Dichloro; 2-[(6-Chloro-2-Methylpyrimidin-4-yl)amino]-N-(2-Chloro-6-Methylphenyl)thiazole-5-Carboxamide
Stock Status In Stock, Production Capacity 15 Tons per Year
CAS Number 302964-08-5
Molecular Formula C16H13Cl2N5OS
Molecular Weight 394.27 g/mol
Melting Point 333.0~335.0℃ 
Density 1.516±0.06 g/cm3 
Store Under Inert Gas Store Under Inert Gas
Sensitive Air Sensitive, Heat Sensitive 
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical

302964-08-5 - Specifications:

Items Specifications  Results
Appearance Off-White to Light Yellow Solid  Complies               
Purity / Analysis Method       >98.0% (HPLC)  99.10%
Infrared Spectrum Consistent with Structure Complies
NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application: Intermediate of Dasatinib (CAS: 302962-49-8) and Dasatinib Monohydrate (CAS: 863127-77-9) 

302964-08-5 - Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

302964-08-5 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

302964-08-5 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

302964-08-5 - Application:

N-(2-Chloro-6-Methylphenyl)-2-[(6-Chloro-2-Methyl-4-Pyrimidinyl)amino]-5-Thiazolecarboxamide (CAS: 302964-08-5), intermediate of Dasatinib (CAS: 302962-49-8) and Dasatinib Monohydrate (CAS: 863127-77-9). Dasatinib is used in all the stages of chronic myelogenous leukemia that have been treated, including Imatinib Mesylate / Gleevec resistant or intolerable (chronic phase, accelerated phase, lymphoid cell blast phase and myeloid leukemia). Cell blast stage) adult patients. At the same time, the FDA has also approved Dasatinib to treat Philadelphia chromosome-positive adult patients with acute lymphoblastic leukemia who are resistant or intolerant to other therapies through normal procedures.

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